Results 241 to 250 of about 32,634,218 (335)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees +6 morewiley +1 more sourceThe temporal stability of (a) carbon content, (b) nitrogen content, (c) phosphorus content, (d) carbon pool, (e) nitrogen pool, (f) phosphorus pool, (g) ratio of carbon to nitrogen (C:N), (h) ratio of carbon to phosphorus (C:P), and (i) ratio of nitrogen to phosphorus (N:P).
Guangyu Zhang (146127), Wei Sun (93580), Shaowei Li (252115), Zhiming Zhong (1745548), Gang Fu (728533) +4 moreopenalex +1 more sourceDual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix +13 morewiley +1 more sourceResults of linear mixed-effects model analysis (F-values, degree of freedom and significance) testing the effects of growing seasons, habitats, soil layers and their interactions on δD, δ18O values of soil and plant leaves of C. gigantea. Data were performed on loge-transformed values. Significant level; *P < 0.05; **P < 0.01; ***P < 0.001.
Yueliang Jiang (20828447), Li Luan (3922202), Youlu Zuo (22319975), Shengyun Liu (9030461), Qiaoling He (492100), Jingyu He (5395640), Ruru Wu (22319978), Gaoming Jiang (287285), Meizhen Liu (287277) +8 moreopenalex +1 more sourceMolecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed +12 morewiley +1 more sourceImpact of Oral Semaglutide on Kidney Outcomes in People With Type 2 Diabetes: Results From the SOUL Randomized Trial. [PDF]
Diabetes CareMann JFE, Marx N, Deanfield JE, Emerson SS, Inzucchi SE, McGuire DK, Mulvagh SL, Pop-Busui R, Poulter NR, Engelmann MDM, Hovingh GK, Belmar N, Idorn T, Jeppesen OK, Birkenfeld AL, Amod A, Mankovsky B, Desouza C, Gorgojo-Martinez JJ, Arechavaleta R, Tu ST, Buse JB, SOUL Study Group*
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