Results 231 to 240 of about 21,813,853 (304)

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

The FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero, Juan Luis Pacheco‐Garcia, Pavla Vankova, Dmitry Loginov, Isabel Quereda‐Moraleda, Jose Manuel Martin‐Garcia, Petr Man, Angel Luis Pey, Milagros Medina   +8 more
wiley   +1 more source

Sex and dose-dependent effects of cannabidiol on cocaine consumption in mice. [PDF]

Transl Psychiatry
Llerena V, Tic I, Llach-Folcrà M, Valverde O, Medrano M.   +4 more
europepmc   +1 more source

Vocabulary Strategy Instruction in the Argentine EFL Context: Teachers’ Perspectives and Practices

International Journal of Applied Linguistics, EarlyView.
ABSTRACT Despite extensive research on vocabulary strategy instruction (VSI), little has been known about teachers’ perspectives on how it is understood and implemented in practice. This study investigated Argentinian EFL teachers’ priorities in vocabulary instruction, their perceived knowledge of learner strategies for spoken vocabulary, and factors ...
Isobel Kai‐Hui Wang, Andrew D. Cohen
wiley   +1 more source

SNUPN-Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights. [PDF]

Ann Clin Transl Neurol
Muelas N, Iruzubieta P, Damborenea A, Pérez-Fernández L, Azorín I, Jiménez García JC, Töpf A, Martí P, Fores-Toribio L, Manterola M, Blanco-Mañez R, Pikatza-Menoio O, Alonso-Martín S, Straub V, Cortajarena AL, López de Munain A, De Sancho D, Blázquez L, Vilchez JJ.   +18 more
europepmc   +1 more source

A fast metaheuristic approach for the planar multiple obnoxious facility location problem

International Transactions in Operational Research, EarlyView.
Abstract The multiple obnoxious facility location problem is one of the most studied problems in the literature of the obnoxious facility location problems family. In this work, we propose an alternative algorithmic approach for this problem, based on an efficient metaheuristic procedure over a discretization of the plane based on Voronoi diagrams ...
Sergio Salazar, Abraham Duarte, J. Manuel Colmenar   +2 more
wiley   +1 more source

Epigenetic, neuroplasticity, and adrenergic targets associated with major depression in immune cells. [PDF]

Sci Rep
Cortés-Erice M, Garayo-Larrea A, Fernández-Ovejero R, Aubá E, Lizaso S, Aldaz P, Bes-Rastrollo M, Gil JL, Barrado L, Ortuño F, Molero P, Tordera RM.   +11 more
europepmc   +1 more source

Evaluation of Nurse‐Led Triage in the Emergency Department: A Retrospective Observational Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To assess the quality of the Spanish Triage System performed by nurses according to the triage code assigned to each patient and to examine factors associated with the need for re‐evaluation after completion of triage. Design Retrospective longitudinal observational study.
Dolores Selva‐Medrano, Jose Alberto Laredo‐Aguilera, Víctor Serrano‐Fernández, Juan Manuel Carmona‐Torres, Ángel López‐González, Inmaculada Pérez‐Rodríguez, Carmen María Guerrero‐Agenjo, Juan David Fernández‐Sánchez, Gloria Mota‐Cátedra, Joseba Rabanales‐Sotos   +9 more
wiley   +1 more source

Single-Cell Profiling Reveals RAB13⁺ Endothelial Cells and Profibrotic Mesenchymal Cells in Aged Human Bone Marrow. [PDF]

Aging Cell
Cenzano I, Cócera M, Lopez-Perez AR, Campos-Dopazo L, Ruiz J, Sancho I, Martin-Uriz PS, Aguirre-Ruiz P, Sarvide S, Vilas-Zornoza A, Ripalda-Cemborain P, Alignani D, Lopez A, Barrios MM, Agreda DQ, Ye J, Lehmann R, Sudupe L, Abengozar-Muela M, Lopez-Janeiro Á, Tamariz-Amador LE, Muiños-López E, Saez B, Tegner J, Calvo IA, Gomez-Cabrero D, Prosper F.   +26 more
europepmc   +1 more source

Voting Red Again: How Social Capital and Local Change Drove the Trump Swing

Journal of Regional Science, EarlyView.
ABSTRACT Social capital has long been regarded as a bulwark of democratic life. Yet in the United States—as across much of the democratic world—some of the communities with the densest social ties have proved the most receptive to antisystem politics.
Pedro Fierro, Andrés Rodríguez‐Pose, Francisco Rowe, Ellen Johanna Helsper   +3 more
wiley   +1 more source

Hidden Fungal Diversity of the Precious Mediterranean Red Coral Corallium rubrum. [PDF]

Environ Microbiol Rep
Prioux C, Carrasco-Acosta M, Prigione V, Venice F, Tignat-Perrier R, Allemand D, Ferrier-Pagès C, Varese GC.   +7 more
europepmc   +1 more source