Results 41 to 50 of about 16,199 (256)

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

open access: yesHepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo   +14 more
wiley   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

open access: yesHepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández   +18 more
wiley   +1 more source

Retos del gobierno electrónico en la transformación digital de la administración pública en Cuba

open access: yesRetos de la Dirección, 2022
Objetivo: Mostrar los retos del gobierno electrónico en base a las perspectivas del desarrollo actual del gobierno digital y a las exigencias de la transformación de la administración pública en Cuba.
Oscar Antonio Wolpes Álvarez
doaj  

El E-Gobierno y la Transformación de la Administración Pública: Experiencias y Lecciones desde la Región Andina

open access: yesCiencia Latina Revista Científica Multidisciplinar, 2023
El gobierno electrónico es el uso de las tecnologías de la información y la comunicación (TIC) para mejorar el funcionamiento del sector público, los servicios a los ciudadanos y la participación democrática. El gobierno electrónico se basa en dispositivos como computadoras e Internet, y se aplica en diferentes niveles de gobierno (local, nacional ...
Noemi Gladys Mencía Sánchez   +3 more
openaire   +1 more source

2D Co‐Mo‐Hydroxide‐Based Multifunctional Material for the Development of H2‐Based Clean Energy Technologies

open access: yesAdvanced Materials, EarlyView.
2D α‐Co(OH)2 interleaved with Mo species displays an appealing dual functionality for the production and use of green hydrogen.Mo incorporation greatly benefits the electrochemical behaviour in Oxygen Evolution Reaction for H2 production, while the magnetocaloric response at liquid H2 temperature paves the way for alternative cryogenic refrigerants ...
Daniel Muñoz‐Gil   +14 more
wiley   +1 more source

Del gobierno electrónico al big data: la digitalización de la gestión pública en Colombia frente al control territorial

open access: yesOpera, 2017
A pesar de sus problemas internos, Colombia es uno de los países latinoamericanos más entusiastas en relación con el gobierno electrónico. Las reformas inducidas por la implementación de políticas alineadas con los odm-ods, así como de la pacificación ...
Miguel Gomis-Balestreri
doaj   +1 more source

Spin‐Split Edge States in Metal‐Supported Graphene Nanoislands Obtained by CVD

open access: yesAdvanced Materials, EarlyView.
Combining STM measurements and ab‐initio calculations, we show that zig‐zag edges in graphene nanoislands grown on Ni(111) by CVD retrieve their spin‐polarized edge states after intercalation of a few monolayers of Au. ABSTRACT Spin‐split states localized on zigzag edges have been predicted for different free‐standing graphene nanostructures.
Michele Gastaldo   +6 more
wiley   +1 more source

Flexoelectrically Induced Polar Topology in Twisted SrTiO3 Membranes

open access: yesAdvanced Materials, EarlyView.
Twisted SrTiO3 bilayers host polar vortices of flexoelectric origin, revealed through combined experiment and theory. By reconstructing polarization from the toroidal moment of strain gradients, the work establishes a 3D chiral state with broken inversion and mirror symmetries.
Isabel Tenreiro   +13 more
wiley   +1 more source

Atomistic Mechanisms Triggered by Joule Heating Effects in Metallic Cu‐Bi Nanowires for Spintronics

open access: yesAdvanced Materials, EarlyView.
Bi doped metallic Cu nanowires are promising for spintronics thanks to the stabilization of a giant spin Hall effect. However, heat resulting from current injection forces Bi to leave solution, forcing segregation into monoatomic decorations which evolve into coherent crystalline aggregates.
Alejandra Guedeja‐Marrón   +6 more
wiley   +1 more source

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