Results 1 to 10 of about 31,819,981 (309)

E-Participation in the Context of Democracy Concept Transformation

open access: yesУправленческое консультирование, 2018
The paper is devoted to the study of «electronic participation» as a special form of social and political participation of citizens in public affairs.
Andrei Vladimirovich Chugunov
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The impact of e-governance on shortening the public service delivery terms

open access: yesTelos: Revista de Estudios Interdisciplinarios en Ciencias Sociales
The impact issue and development of e-governance on shortening the terms of public service provision is urgent for ensuring the efficiency of government agencies. The public service delivery terms affect the effectiveness of the state's public policy and
Oleh Lazor   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Assisting Coastal and Marine Governance: Enhancing Decision Support Through Digital Tools for Cumulative Impact Assessment

open access: yesOcean and Society
Coastal regions are increasingly pressured by diverse human activities, leading to cumulative effects that undermine ecosystem integrity and functioning, including disruptions to biodiversity, habitat degradation, and alterations of ecological processes.
Jonne Kotta   +8 more
doaj   +1 more source

Problems of providing information security in the system of public administration

open access: yesAspekti Publìčnogo Upravlìnnâ, 2018
The article analyzes the scientific approaches to the problem of providing information security of the public administration system. It was determined that information security in the system of public administration is an integral part of the national ...
Y. I. Chmyr
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Digital model for monitoring national programs: the Kazakhstan experience

open access: yesFrontiers in Artificial Intelligence
This paper presents a conceptual digital model for monitoring national programs designed to enhance their effectiveness, transparency, and performance in the context of digital transformation in public administration.
Mafura Uandykova   +5 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

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