Results 101 to 110 of about 95,805 (288)
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
The role of affective information in the sociomoral development of preschool children
, 1993 Early theories of social-cognitive development emphasized children\u27s unilateral respect for rules and authority (Piaget, 1932/65). Recently, however, children have been found to make conceptual distinctions among moral, conventional, and personal ...
Wiersma, Noelle Susanna
core +1 more source
THE TRANSFORMATIVE POWER OF THE EU-UKRAINE DCFTA: EVIDENCE FROM THE ONGOING DEREGULATION REFORM IN UKRAINE [PDF]
CES Working Papers, 2016 The lack of genuine transformative power in the region was repeatedly distinguished as a major weakness of the Eastern Partnership (EaP) in Ukraine. However, the intensity and comprehensiveness of ongoing reform processes cause the need to revise the ...
Maryna Rabinovych
doaj
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Electronic governance, premise for implementation of electronic democracy [PDF]
Living in a rapidly changing society, where information travels with great speed and its upgrade is essential, we decided to approach certain aspects of e-democracy, as a dynamic way of citizen participation, using new Information and Communications ...
Grigorovici, Iulia, Matei, Ani
core +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Aging and Cancer, EarlyView.This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
e-Justice Governance in the EU
Technology use has been seen as a way to make access to justice easier, faster, and more efficient. In the EU, e-justice actions have been centred around supporting activities leading to building up access to legal information, access to courts and extrajudicial procedures in a cross-border setting, and communication between judicial authorities. These
openaire +2 more sources