Results 91 to 100 of about 32,759,036 (278)

Environmental Protection, Producer Insolvency and Lender Liability [PDF]

open access: yes
The present paper deals with some legal issues surrounding environmental protection, namely those issues concerning the liability of the different firms and individuals directly or indirectly involved in the generation of environment damaging accidents ...
Jean-Jacques Laffont, Marcel Boyer
core  

An Oral Antiviral Combination Against Severe COVID‐19 Enabled by the Synergistic Mechanisms of Action of Auranofin and Remdesivir

open access: yesAdvanced Science, EarlyView.
FDA‐approved anti‐inflammatory drug Auranofin inhibits SARS‐CoV‐2 replication by inhibiting viral Main protease activity and Spike processing required for viral entry. It shows strong synergy with nucleoside analogue Remdesivir, due to non‐overlapping mechanisms.
Oyahida Khatun   +13 more
wiley   +1 more source

Therapeutic Peptide‐Programmed Liquid‐Crystalline Topology Switching for pH‐Gated Postoperative Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A VDAP‐programmed liquid‐crystalline depot enables pH‐responsive postoperative immunotherapy for triple‐negative breast cancer. VDAP stabilizes a leakage‐resistant HII mesophase through peptide–lipid electrostatic assembly, whereas tumor acidosis unlocks the matrix and promotes graded topology remodeling toward a bicontinuous Im3̄m cubic phase for ...
Yan Yan   +12 more
wiley   +1 more source

Polyphosphate Copper Nanospheres Drive Mitochondrial Metabolic Reprogramming via Calcium Phase Separation for Self‐Sensitizing Cuproptosis

open access: yesAdvanced Science, EarlyView.
This study developed polyphosphate (polyP)‐based nanostructures that enable calcium‐mediated metabolic reprogramming via liquid–liquid phase separation (LLPS). Released polyP undergoes LLPS with Ca2+, suppressing glycolytic flux and enhancing mitochondrial metabolism effectively.
Jing Wang   +10 more
wiley   +1 more source

Risk, Informational Asymmetry and Product Liability; An enquiry into conflicting objectives [PDF]

open access: yes
Risky products cause two types of costs for society; the accident costs and the insurance costs. Liability rules allocate these costs between the parties involved.
Ram Singh
core  

Disrupted Top‐Down Modulation as a Mechanism of Impaired Multisensory Processing in Autistic Children

open access: yesAdvanced Science, EarlyView.
In this work, we show that multisensory integration in autistic children is characterized by attenuated ERP responses and α‐band desynchronization, together with reduced theta‐band communication between parieto‐occipital and frontal regions. The intermediate neural profile observed in unaffected siblings raises the possibility that altered cortical ...
Theo Vanneau   +3 more
wiley   +1 more source

Switching Consumers and Product Liability: On the Optimality of Incomplete Strict Liability [PDF]

open access: yes
This article shows that it may be socially optimal to grant accident victims less than full compensation. In our framework, firms are liable under product liability but also invest in care to prevent consumers switching to competitors.
Tim Friehe   +2 more
core  

Stochastic‐MTJ Sampler Arrays for In‐Array Monte–Carlo Estimation

open access: yesAdvanced Electronic Materials, EarlyView.
A low‐energy‐barrier magnetic tunnel junction array is operated as a probability‐domain sampler: each cell's random switching, programmed through a shared digital‐to‐analog converter, makes the per‐column multiply–accumulate an unbiased Monte–Carlo expectation estimator that returns both a mean and a calibrated uncertainty.
Ran Zhang   +6 more
wiley   +1 more source

Discovery of hydrocarbon source rocks in the Permian Xinxing Formation in the southern Zhangguangcai range, Northeast China

open access: yesChina Geology, 2019
Mi-shan Zhong   +10 more
doaj   +1 more source

Optimal liability sharing and court errors: an exploratory analysis [PDF]

open access: yes
We focus in this paper on the effects of court errors on the optimal sharing of liability between firms and financiers, as an environmental policy instrument. Using a structural model of the interactions between firms, financial institutions, governments
Donatella Porrini, Marcel Boyer
core  

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