Results 71 to 80 of about 86,577 (302)

An E-Liquid Flavor Wheel: A Shared Vocabulary Based on Systematically Reviewing E-Liquid Flavor Classifications in Literature [PDF]

open access: yesNicotine & Tobacco Research, 2018
AbstractIntroductionE-liquids are available in a high variety of flavors. A systematic classification of e-liquid flavors is necessary to increase comparability of research results. In the food, alcohol, and fragrance industry, flavors are classified using flavor wheels.
Krüsemann, Erna J.Z.   +3 more
openaire   +4 more sources

Identification of “Kratom” (Mitragyna speciosa) Alkaloids in Commercially Available Products [PDF]

open access: yes, 2017
“Kratom” is the common name for the botanical mitragyna speciosa. It is a tree native to Southeast Asia in which leaves contain the psychoactive alkaloids mitragynine and 7-hydroxymitragynine. Kratom is often ingested as teas, chewed, or smoked.
Grzymkowski, Julia   +2 more
core   +1 more source

Social Bots for Online Public Health Interventions

open access: yes, 2018
According to the Center for Disease Control and Prevention, in the United States hundreds of thousands initiate smoking each year, and millions live with smoking-related dis- eases. Many tobacco users discuss their habits and preferences on social media.
Allem, Jon-Patrick   +7 more
core   +1 more source

New Tobacco and Tobacco-Related Products: Early Detection of Product Development, Marketing Strategies, and Consumer Interest. [PDF]

open access: yes, 2018
A wide variety of new tobacco and tobacco-related products have emerged on the market in recent ...
Havermans, Anne   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

An ingredient co-occurrence network gives insight into e-liquid flavor complexity

open access: yesTobacco Induced Diseases
Introduction Part of the appeal of e-cigarettes lies in their available flavors. To achieve attractive flavors, e-liquids contain many different flavoring agents, which allow many flavoring combinations.
Jeroen L. A. Pennings   +3 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

After 20 Years on the Market: The Current Outlook on E-Cigarette Use Among Youth

open access: yesJournal of Medical Science
Introduction. Electronic nicotine dispensing systems, commonly known as e-cigarettes, remain the most widely used tobacco product among the youth, with current worldwide use estimated at approximately 5 to 7%.
Katarzyna Drewnowska   +10 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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