Results 111 to 120 of about 41,889,929 (253)

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

RFID Technology and Its Industrial Applications

, 2011
In this chapter, we give a detailed introduction of radio frequency identification (RFID) technology and 15 different applications for different industries. We introduce RFID transponders, readers, middleware, and labels.
Chang, E, Potdar, V, Sharif, A
core   +1 more source

Image Sensors in Security and Medical Applications [PDF]

, 2007
This paper briefly reviews CMOS image sensor technology and its utilization in security and medical applications. The role and future trends of image sensors in each of the applications are discussed.
Yadid-Pecht, Orly, Fish, Alexander, Artyomov, Evgeny   +2 more
core   +1 more source

Chitosan from shrimp shell waste as a carrier for frankincense nanoparticles with enhanced antimicrobial activity

Scientific Reports
This study focuses on the sustainable extraction of chitosan from shrimp shell waste and its application in developing frankincense-loaded chitosan nanoparticles with enhanced antimicrobial efficacy. Chitosan was extracted through demineralization with 4%
Habiba A. Ahmed, Zeinab A. Salama, Abeer E. Abd El-Wahab, Ahmed M. Aboul-Enein, Amr Nassrallah   +4 more
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Multiple Case Study Investigation of E-Reader Devices in Academia

, 2012
E-texts are seen as the imminent direction for education publishers. There are many e-reader devices currently available, leading to a variety of device characteristics that might affect use of the device, and more importantly, impact behaviors that can ...
Scharff, Lauren
core  

Accessing e-Learning Systems via Screen Reader: An Example

, 2009
The evolution of the Information and Communication Technology (ICT) and the rapid growth of the Internet have impelled the pervasive diffusion of e-Learning systems.
Buzzi M, Leporini B, Marina Buzzi, Buzzi M C, Barbara Leporini, Maria Claudia Buzzi, Buzzi MC   +6 more
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Development and clinical validation of deep learning-based immunohistochemistry prediction models for subtyping and staging of gastrointestinal cancers

BMC Gastroenterology
Background Immunohistochemistry (IHC) is a critical tool for tumor diagnosis and treatment, but it is time and tissue consuming, and highly dependent on skilled laboratory technicians.
Junxiao Wang, Shiying Zhang, Jia Li, Mei Deng, Zhi Zeng, Zehua Dong, Fangfang Chen, Wen Liu, Lianlian Wu, Honggang Yu   +9 more
doaj   +1 more source