Results 181 to 190 of about 71,913,510 (296)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Correction: SARS‑CoV‑2 envelope protein triggers depression‑like behaviors and dysosmia via TLR2‑mediated neuroinflammation in mice. [PDF]

J Neuroinflammation
Su W, Ju J, Gu M, Wang X, Liu S, Yu J, Mu D.   +6 more
europepmc   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Corrigendum to "Impact of L-citrulline on meat production and quality: A study on its effects on meat attributes and nutritional composition" [Poultry Science, Volume 104, Issue 12, December 2025, 106039]. [PDF]

Poult Sci
Bhuiyan MIH, Ahmed MJ, Mamun M, Islam K, Chalise R, Bhandari P, Alam KE, Kaderi IJ, Alam MJ, Hossain D, Ali M.   +10 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Ciência e destruição Science and destruction

Estudos Avançados, 2010
Carlos Malferrari
doaj   +1 more source

LncRNA Gas5 directs SUV39H2 to establish heterochromatin and maintain genome stability. [PDF]

Protein Cell
Liu J, Yang J, Ye W, Zhang D, Su N, Wang H, Zhang Y, Gao S, Kang L.   +8 more
europepmc   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Lattice Parameter Governs Magnetic Ground State Selection in Tsai-Type Intermetallic Compounds. [PDF]

J Am Chem Soc
Labib F, Nawa K, Nambu Y, Takakura H, Ikeda Y, Deguchi K, Matsuura M, Ishikawa A, Kajimoto R, Ikeuchi K, Sato TJ, Tamura R.   +11 more
europepmc   +1 more source