Results 41 to 50 of about 48,074,105 (310)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

O processo de construção da Política de Governança de Dados, Informação e Conhecimento da Embrapa

open access: yesCiência da Informação, 2020
Dados, informação e conhecimento são ativos corporativos valiosos e, por isso, devem ser bem governados e geridos de modo a maximizar o seu valor. Um dos mecanismos de governança é a implementação de políticas, que são instrumentos formais onde estão ...
Patrícia Rocha Bello Bertin   +1 more
doaj  

Digitalisation Guide Book of Basic Physics Practicum Equilibrium Material

open access: yesJurnal Teknologi Pendidikan, 2021
This article presents research on inquiry-based e-modules for science process skills. This lab module is made with stages of development, implementation and evaluation adopted from branch.
Tanti   +3 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Topology Aggregation for E-science Networks [PDF]

open access: yes2010 10th IEEE/ACM International Conference on Cluster, Cloud and Grid Computing, 2010
We propose several algorithms for topology aggregation (TA) to effectively summarize large-scale networks. These TA techniques are shown to significantly better for path requests in e-Science that may consist of simultaneous reservation of multiple paths and/or simultaneous reservation for multiple requests.
Eun-Sung Jung   +2 more
openaire   +2 more sources

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Essential Readings in e-Science

open access: yesIssues in Science and Technology Librarianship, 2011
The amount of data that scientists produce continues to increase every year. People are needed to handle, preserve, describe, and organize that data, and, because many of these tasks are similar to what librarians have done with publications for ...
Kathy Szigeti, Kathy Wheeler
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

E-Science Librarianship: Field Undefined.

open access: yesIssues in Science and Technology Librarianship, 2011
The potential of librarians working in e-science, a term for using the Internet and other digital tools to facilitate scientific data collection, management, and sharing, has been the cause of much discussion.
Elsa Alvaro   +2 more
doaj   +1 more source

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