Results 111 to 120 of about 21,905,570 (280)

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

open access: yesThe FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero   +8 more
wiley   +1 more source

Criterios para el tratamiento del Sector Servicios en el marco de la ALADI

open access: yes, 1986
ALADI. Comité de Coordinación y Negociaciones.
ALADI. Comité de Coordinación y Negociaciones. Subcomité 2: Servicios
core   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

open access: yesThe FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti   +3 more
wiley   +1 more source

Factors associated on head, face and neck region injuries in recreational surfers in Acapulco, Mexico.

open access: yesRevista de la Facultad de Medicina Humana
Introduction: Surfing carries potential and significant risk of head and face injuries in almost half of the surfers admitted to emergency departments. Objective: To estimate the frequency of head, face and neck injuries and identify associated factors ...
Carlos Alberto Juárez Medel   +6 more
doaj   +1 more source

Imaging Point Source Groundwater Discharges in a Confined Coastal Aquifer Using Electrical Resistivity

open access: yesGroundwater, EarlyView.
Marine electrical resistivity tomography (ERT) is applied to characterize point‐source submarine groundwater discharge (PSGD) along NW Yucatán. ERT observations and forward modeling constrain conduit detectability under varying hydrogeological conditions.
Mariana Gómez‐Nicolás   +6 more
wiley   +1 more source

Simposio Suramericano de Servicios Públicos de Empleo [PDF]

open access: yes, 1995
Se presentan las memorias de las intervenciones de los representantes de diversos países en el Simposio Suramericano de Servicios Públicos de Empleo desarrollado en Bogotá en 1995.Reports of the interventions of the representatives of various countries ...

core  

Real‐World Unmet Treatment Needs for Patients With Haemophilia: Results From the Global Adelphi Disease Specific Programme Database

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Prophylactic factor replacement and non‐factor therapy has improved bleed prevention and clinical outcomes for people with haemophilia (PwH). The remaining burdens faced by PwH in real‐world settings, despite availability of newer therapies, are not well documented.
Víctor Jiménez Yuste   +5 more
wiley   +1 more source

Hodgkin and non‐Hodgkin lymphomas in the post‐antiretroviral therapy era according to HIV virological suppression

open access: yesHIV Medicine, EarlyView.
Abstract Objectives Lymphomas remain among the most frequent HIV‐associated malignancies, with risk persisting despite effective virological control. This study describes the clinical, epidemiological and prognostic characteristics of lymphomas (both Hodgkin [HL] and non‐Hodgkin [NHL]) in people living with HIV (PLWH), according to virological ...
Teresa Aldámiz‐Echevarria   +555 more
wiley   +1 more source

Petición N° 1-0000034779 ¿En virtud del régimen jurídico según el cual las cámaras de comercio cobran por sus servicios registrales, podría proceder la devolución de esos costos?

open access: yes, 2014
¿En virtud del régimen jurídico según el cual las cámaras de comercio cobran por sus servicios registrales, podría proceder la devolución de esos costos?Servicios registralesLas cámaras de comercio, están en la obligación de cobrar a los empresarios por ...
Cámara de Comercio de Bogotá   +1 more
core  

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