Results 11 to 20 of about 337,095 (287)
E1, an ATP-dependent DNA helicase, is the only enzyme encoded by papillomaviruses (PVs). It is essential for replication and amplification of the viral episome in the nucleus of infected cells. To do so, E1 assembles into a double-hexamer at the viral origin, unwinds DNA at the origin and ahead of the replication fork and interacts with cellular DNA ...
Bergvall, Monika +2 more
openaire +3 more sources
Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in sumo pathways [PDF]
Canonical ubiquitin-like proteins (UBLs) such as ubiquitin, Sumo, NEDD8, and ISG15 are ligated to targets by E1-E2-E3 multienzyme cascades. The Sumo cascade, conserved among all eukaryotes, regulates numerous biological processes including protein ...
Miller, D.J. +31 more
core +2 more sources
Cell proliferation was significantly decreased in full-length HPV16 E1 (pEGFP-E1) transfected cells.
Cell proliferation of pEGFP, vector control, full-length HPV16 E1 (pEGFP-E1) and truncated forms of HPV16 E1 (pEGFP-E1-184, pEGFP-E1-359, and pEGFP-E1-439).
Shankar Varadarajan (282529) +3 more
core +1 more source
Functional processing and secretion of Chikungunya virus E1 and E2 glycoproteins in insect cells [PDF]
Background: Chikungunya virus (CHIKV) is a mosquito-borne, arthrogenic Alphavirus that causes large epidemics in Africa, South-East Asia and India. Recently, CHIKV has been transmitted to humans in Southern Europe by invading and now established Asian ...
Geertsema, C (Corinne) +44 more
core +2 more sources
REGIONAL CHALLENGES IN THE DEVELOPMENT OF AGRICULTURAL POLICY IN GEORGIA [PDF]
The modern world has entered an acute phase of irreversible changes and implementation of global economic transformation. In today's situation, a sensible, coherent, flexible and adaptable national economic strategic doctrine created by the state ...
Paata Koghuashvili, Niko Chikhladze
doaj +1 more source
The paper analyses and experimentally verifies deployment of Ethernet based network technology to enable fault tolerant and timely exchange of data among a number of high voltage protective relays that use proprietary serial communication line to ...
Leos Bohac, Jiri Vodrazka
doaj +1 more source
Ectopic scrotum: Single stage rotational flap reconstruction with orchidopexy
Introduction: Congenital anomalies of the scrotum are rare; furthermore, ectopic scrotum and accessory scrotum are rarer still. We describe our series of four cases with their surgical management and long-term outcomes.
Rashmi R. Singh +4 more
doaj +1 more source
TELECOMMUTING IN GEORGIAN HIGHER EDUCATION SYSTEM – CHALLENGES AND OPPORTUNITIES [PDF]
Georgian universities as business entities are faced with new reality provoked by Covid-19. Distance learning became accompanying part of teaching as providing service to students.
Giorgi Butskhrikidze, Neli Beridze
doaj +1 more source
Financialization and the Labor Share of Income
Financialization has been growing importance in macroeconomic perspectives since the finance-dominated capitalist relations have captured many of the specific positions in an aggregate economy.
Özdemir Onur
doaj +1 more source
Objective: The COVID-19 pandemic led to a dramatic decrease in face-to-face teaching. This can particularly impact medical students' skills development.
Louise Kuo, MBBS, iBSc +4 more
doaj +1 more source

