Results 11 to 20 of about 309,262 (293)
E1, an ATP-dependent DNA helicase, is the only enzyme encoded by papillomaviruses (PVs). It is essential for replication and amplification of the viral episome in the nucleus of infected cells. To do so, E1 assembles into a double-hexamer at the viral origin, unwinds DNA at the origin and ahead of the replication fork and interacts with cellular DNA ...
Bergvall, Monika +2 more
openaire +3 more sources
In Vitro and In Vivo Biology of Recombinant Adenovirus Vectors with E1, E1/E2A, or E1/E4 Deleted [PDF]
ABSTRACT Isogenic, E3-deleted adenovirus vectors defective in E1, E1 and E2A, or E1 and E4 were generated in complementation cell lines expressing E1, E1 and E2A, or E1 and E4 and characterized in vitro and in vivo. In the absence of complementation, deletion of both E1 and E2A completely abolished expression of early and late viral genes ...
M, Lusky +9 more
openaire +2 more sources
TELECOMMUTING IN GEORGIAN HIGHER EDUCATION SYSTEM – CHALLENGES AND OPPORTUNITIES [PDF]
Georgian universities as business entities are faced with new reality provoked by Covid-19. Distance learning became accompanying part of teaching as providing service to students.
Giorgi Butskhrikidze, Neli Beridze
doaj +1 more source
PECULIARITIES OF CONSUMER BEHAVIOR IN THE PROCESS OF PURCHASING RAW BEEF AND PORK [PDF]
Anticipating consumer behavior is one of the key issues in modern marketing. Since consumers are the main target of any company or organization, enterprise, or trader, and the final link in a value chain, it is important to study and analyze the factors ...
Tea Valishvili, Elguja Deisadze
doaj +1 more source
ACTUAL ISSUES OF ASSESSMENT OF THE INVESTMENT ENVIRONMENT [PDF]
One of the most important factors of the sustainable and safe development of the national economy is the availability of investment resources in the economy, the establishment of a favorable climate for attracting foreign investments and the mechanisms ...
Ramin Tsinaridze +2 more
doaj +1 more source
THE ROLE FOR DEVELOPMENT OF AQUACULTURE IN ECONOMIC GROWTH OF SAMTSKHE-JAVAKHETI REGION OF GEORGIA [PDF]
The article presents the analytical description of the current situation of aquaculture development in Samtskhe-Javakheti region and in Georgia in general.
Lavrenti Chiburdanidze +1 more
doaj +1 more source
Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in sumo pathways [PDF]
Canonical ubiquitin-like proteins (UBLs) such as ubiquitin, Sumo, NEDD8, and ISG15 are ligated to targets by E1-E2-E3 multienzyme cascades. The Sumo cascade, conserved among all eukaryotes, regulates numerous biological processes including protein ...
Miller, D.J. +31 more
core +1 more source
Cell proliferation was significantly decreased in full-length HPV16 E1 (pEGFP-E1) transfected cells.
Cell proliferation of pEGFP, vector control, full-length HPV16 E1 (pEGFP-E1) and truncated forms of HPV16 E1 (pEGFP-E1-184, pEGFP-E1-359, and pEGFP-E1-439).
Shankar Varadarajan (282529) +3 more
core +1 more source
Functional processing and secretion of Chikungunya virus E1 and E2 glycoproteins in insect cells [PDF]
Background: Chikungunya virus (CHIKV) is a mosquito-borne, arthrogenic Alphavirus that causes large epidemics in Africa, South-East Asia and India. Recently, CHIKV has been transmitted to humans in Southern Europe by invading and now established Asian ...
Geertsema, C (Corinne) +44 more
core +1 more source
The paper analyses and experimentally verifies deployment of Ethernet based network technology to enable fault tolerant and timely exchange of data among a number of high voltage protective relays that use proprietary serial communication line to ...
Leos Bohac, Jiri Vodrazka
doaj +1 more source

