Results 11 to 20 of about 9,908 (120)

Circ-PNPT1 contributes to gestational diabetes mellitus (GDM) by regulating the function of trophoblast cells through miR-889-3p/PAK1 axis

Diabetology & Metabolic Syndrome, 2021
Background Gestational diabetes mellitus (GDM) is the most common medical complication of pregnancy. CircRNA polyribonucleotide nucleotidyltransferase 1 (circ-PNPT1) has been found to be abnormally expressed in GDM patients.
Li Zhang, Mingyang Zeng, Fei Tang, Jun Chen, Dongmei Cao, Ze-nan Tang   +5 more
semanticscholar   +1 more source

Silencing of hsa_circ_0009035 Suppresses Cervical Cancer Progression and Enhances Radiosensitivity through MicroRNA 889-3p-Dependent Regulation of HOXB7

Molecular and Cellular Biology, 2021
Circular RNAs (circRNAs), a novel type of endogenous noncoding RNAs, have been identified as critical regulators in human carcinogenesis. Here, we investigated the precise actions of hsa_circ_0009035 in the progression and radioresistance of cervical ...
Xia Zhao, Weilei Dong, Gui-fang Luo, Jing Xie, Jie Liu, Furong Yu   +5 more
semanticscholar   +1 more source

MicroRNA-889-3p restrains the proliferation and epithelial–mesenchymal transformation of lung cancer cells via down-regulation of Homeodomain-interacting protein kinase 1

Bioengineered, 2021
Dysregulated microRNAs (miRNAs) are common in human cancers and are involved in the proliferation, promotion, and metastasis of tumor cells. Therefore, the aim of this study was to evaluate the expression and biological function of miR-889-3p in lung ...
Qiang Zhu, Yun Li, Lina Li, Ming Guo, Chenxi Zou, Yi Xu, Zhen Yang   +6 more
semanticscholar   +1 more source

Enhanced expression of miR-889 forecasts an unfavorable prognosis and facilitates cell progression in hepatocellular carcinoma

Diagnostic Pathology, 2021
Background As a new type of molecular marker, microRNAs (miRNAs) can be used for early diagnosis and prognosis prediction of malignant tumors, and has broad clinical application prospects.
He Wang, Huiwen Wang, Wenyu Cui, Qiao-Lin Zhang, Jing Li, Qi Zhang   +5 more
semanticscholar   +1 more source

A New Stellar Companion to TYC 5493-889-1

Research Notes of the AAS, 2021
We present a serendipitous discovery of a new stellar companion to TYC 5493-889-1 detected with the Differential Speckle Survey Instrument at the 4.3 m Lowell Discovery Telescope.
C. Clark, G. V. van Belle, E. Horch
semanticscholar   +1 more source

MicroRNA-889 Inhibits Autophagy To Maintain Mycobacterial Survival in Patients with Latent Tuberculosis Infection by Targeting TWEAK

mBio, 2020
TB remains a leading cause of morbidity and mortality worldwide. Approximately one-quarter of the world’s population has latent TB infection. TWEAK is a multiple-function cytokine and may be used as a target for the treatment of rheumatic diseases ...
Der-Yuan Chen, Yi-Ming Chen, Chin-Fu Lin, Che-Min Lo, Hung-Jen Liu, Tsai-Ling Liao   +5 more
semanticscholar   +1 more source

Is Truth to Post-Truth what Modernism Is to Postmodernism? Heidegger, the Humanities, and the Demise of Common-Sense

European Journal of American Studies, 2020
This essay argues that there is no such thing as post-truth. We are by no means in the middle of an unprecedented epistemological crisis that keeps us from telling right from wrong.
Klaus Benesch
doaj   +1 more source

NNT-AS1 in CAFs-derived exosomes promotes progression and glucose metabolism through miR-889-3p/HIF-1α in pancreatic adenocarcinoma

Scientific Reports
It is metabolic and signaling crosstalk between stromal cells and tumors in the tumor microenvironment, which influences several aspects of tumor formation and drug resistance, including metabolic reprogramming.
Pingping Zhang, Qun Wang, Weijun Lu, Feng Zhang, Dongde Wu, Junwei Sun   +5 more
semanticscholar   +1 more source

miR-889-3p targeting BMPR2 promotes the development of retinoblastoma via JNK/MAPK/ERK signaling

Scientific Reports
MicroRNAs (miRNAs) are vital regulators of tumor pathogenesis, including that of retinoblastoma (Rb). This study investigated the functions and mechanisms of action of miR-889-3p in Rb.
Yuan Gao, Pei Du
semanticscholar   +1 more source

MicroRNA-889-3p targets FGFR2 to inhibit cervical cancer cell viability and invasion.

Experimental and Therapeutic Medicine, 2019
MicroRNAs (miRNAs) are frequently dysregulated in cervical cancer, and the aberrant regulation of miRNAs may be involved in the regulation of various cancer-associated biological processes.
Yu Sun, Yan Cheng, Y. Zhang, Kun Han
semanticscholar   +1 more source