Results 251 to 260 of about 1,377,203 (295)

Lipids are essential for potassium transport by KdpFABC from E. coli

open access: yes
Hussein A   +4 more
europepmc   +1 more source

Stereochemistry of 1,2-elimination reactions at the E2–E1cB interface—tert-butyl 3-tosyloxybutanoate and its thioester

Organic & Biomolecular Chemistry, 2008
Experimental data on the stereoselectivity of base-catalyzed 1,2-elimination reactions that produce conjugated carbonyl compounds are scarce in spite of the importance of these reactions in organic and biochemistry. As part of a comprehensive study in this area, we have synthesized stereospecifically-deuterated beta-tosyloxybutanoate esters and ...
Jerry R, Mohrig   +8 more
openaire   +2 more sources

C-DLTS interface defects in Al0.22Ga0.78N/GaN HEMTs on SiC: Spatial location of E2 traps

Physica E: Low-dimensional Systems and Nanostructures, 2018
Abstract The purpose of this paper has focused on the investigation of the High electron mobility transistors AlGaN/GaN HEMTs based on SiC substrates by means of capacitance-voltage-temperature (C-V-T) and Deep Level Transient Spectroscopy (DLTS). The C-V analysis have been recorded in the 20–320 K temperature range and exhibit an increase in
I. Jabbari   +3 more
openaire   +1 more source

Prostaglandin E 2 – EP4 Signaling at the Gut–Immune–Metabolic Interface: A Lipid Mediator Perspective on Obesity and Insulin Resistance

Comprehensive Physiology
ABSTRACT Despite advances in dietary and pharmacologic therapies, obesity rates continue to escalate globally. Emerging evidence implicates the gut–immune interface as a key determinant of metabolic dysfunction. This review highlights the prostaglandin E 2 (PGE
Nila Ganamurali, Sarvesh Sabarathinam
openaire   +2 more sources

De Novo Design and Computational Validation of a High-Affinity Peptide Inhibitor Targeting the HPV E1-E2 Interface

Abstract The oncogenic progression of high-risk Human Papillomavirus (HPV) strains relies on the cooperative interaction between the E1 replicative helicase and the E2 origin-binding protein to initiate viral DNA amplification. Disrupting this protein-protein interaction represents a promising, yet clinically unrealized, therapeutic ...
Sean Fletcher   +2 more
openaire   +1 more source

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