Results 71 to 80 of about 4,345 (206)

Peptides inhibiting the assembly of monomeric human l‐lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells

open access: yesProtein Science, Volume 33, Issue 10, October 2024.
Abstract The energetic metabolism of cancer cells relies on a substantial commitment of pyruvate to the catalytic action of lactate‐generating dehydrogenases. This coupling mainly depends on lactate dehydrogenase A (LDH‐A), which is overexpressed in different types of cancers, and therefore represents an appealing therapeutic target.
Alessandra Stefan   +14 more
wiley   +1 more source

Characterization of antimicrobial resistance profiles in Escherichia coli isolated from captive mammals in Ecuador

open access: yesVeterinary Medicine and Science, Volume 10, Issue 4, July 2024.
Among 90 E. coli isolates from 70 mammals, significant resistance was found to ampicillin (52.22%), ceftriaxone (42.22%) and cefuroxime (42.22%), with 27.78% being ESBL‐producing. Notably, 66.67% of isolates showed resistance to at least one antibiotic, and 35.56% exhibited multiresistant phenotypes.
Anabell Medina   +9 more
wiley   +1 more source

El coste del déficit público en España: el aumento en las tasas impositivas y la reducción del gasto público

open access: yesEl Trimestre Económico, 2018
Antecedentes: En los últimos siete años la economía española ha tratado de reducir el ratio de déficit público-PIB de 11.1% en 2009 a 3%. Este valor es un compromiso registrado en el Pacto de Estabilidad y Crecimiento firmado por todos los ...
María T. Álvarez-Martínez   +1 more
doaj   +1 more source

The Invisible Hand of the Government: 'Moral Suasion' During the European Sovereign Debt Crisis

open access: yesAmerican Economic Journal: Macroeconomics, 2016
Using proprietary data on banks’ monthly securities holdings, we show that during the European sovereign debt crisis, domestic banks in fiscally stressed countries were considerably more likely than foreign banks to increase their holdings of domestic ...
S. Ongena, A. Popov, Neeltje van Horen
semanticscholar   +1 more source

Drivers of Greek and Turkish Defense Spending

open access: yesInternational Journal of Management and Economics, 2016
This paper evaluates the factors responsible for maintaining substantial military expenditures in Greece and Turkey. The presented research encompasses theoretical and empirical aspects.
Waszkiewicz Grzegorz
doaj   +1 more source

Bis(2-aminopyridine)dibenzoatocobalt(II). Erratum

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2016
In the paper by Ju et al. [Acta Cryst. (2006), E62, m1012–m1013], the metal atom was reported incorrectly.
Wen-Zheng Ju   +3 more
doaj   +1 more source

The Taxing Challenges of the State: Unveiling the Role of Fiscal and Administrative Capacity in Development

open access: yesCESifo Economic Studies
The growing emphasis on nation-states and their pivotal role in economic development has emerged as a central theme in contemporary economic discourse. This review examines the concept of state capacity as discussed in the economic literature, focusing
Federica Braccioli   +3 more
semanticscholar   +1 more source

Fiscal Federalism, Tax Independence and Social Enhancement

open access: yesStudia Universitatis Vasile Goldis Arad, Seria Stiinte Economice, 2022
The tax autonomy of Nigeria’s three tiers of government is examined in this study to estimate the value of revenue fiscal decentralization in increasing citizens’ social welfare.
Omodero Cordelia Onyinyechi
doaj   +1 more source

A machine learning projection method for macro‐finance models

open access: yesQuantitative Economics, Volume 15, Issue 1, Page 145-173, January 2024.
We use supervised machine learning to approximate the expectations typically contained in the optimality conditions of an economic model in the spirit of the parameterized expectations algorithm (PEA) with stochastic simulation. When the set of state variables is generated by a stochastic simulation, it is likely to suffer from multicollinearity.
Vytautas Valaitis, Alessandro T. Villa
wiley   +1 more source

Difficulties in testing for capital overaccumulation

open access: yesQuantitative Economics, Volume 15, Issue 1, Page 89-114, January 2024.
This paper reconsiders the question of testing for the presence of Pareto suboptimal capital overaccumulation in overlapping generations economies. The paper allows generation‐specific technology shocks to evolve over time according to a stationary Markov chain, and assumes that an econometrician observes a finite sample of aggregate quantities.
Narayana R. Kocherlakota
wiley   +1 more source

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