Results 31 to 40 of about 18,774 (187)

A Novel Topical Emollient Plus for Canine Atopic Dermatitis: A Clinical Trial Assessing Efficacy and User Acceptance

Veterinary Dermatology, Volume 37, Issue 2, Page 293-305, April 2026.
Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes, António Caldeira Mendes, Susana Paula Alves, Vanessa Schmidt, Ana Filipa Bizarro, Marta Pinto, Hugo Pereira, Joana Marto, Ana Mafalda Lourenço   +8 more
wiley   +1 more source

Efficacy of Der f 2/Zen 1‐LAMP1 Plasmid‐Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof‐of‐Concept Study

Veterinary Dermatology, Volume 37, Issue 2, Page 306-318, April 2026.
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova, Chigusa Matsumoto, Shoji Ogino, Toshihiro Tsukui, Kim Love, Marcy Murphy, Ina Herrmann   +6 more
wiley   +1 more source

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

Advanced Science, Volume 13, Issue 18, 27 March 2026.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding, Ling Jiang, Yijia Song, Zhongji Pu, Lirong Yang, Haoran Yu   +5 more
wiley   +1 more source

Emerging evidence supports direct-acting antiviral therapy for HCC patients beyond the early stage: Correspondence to editorial on “Direct-acting antiviral therapy for patients with HCV-related hepatocellular carcinoma: A nationwide cohort study” [PDF]

Clinical and Molecular Hepatology
Teng-Yu Lee, Pei-Chien Tsai, Shou-Wu Lee, Ming-Lung Yu   +3 more
doaj   +2 more sources

Determinants of Individual Performance of Professional Village Facilitators: The Mediation of Innovative Work Behavior and Moderation of Work-Life Balance in Kediri Regency, Indonesia

ECONOMICS
This study explores the critical role of innovative work behavior in mediating the effects of job crafting and work integrity on individual performance among professional village facilitators in Kediri Regency, Indonesia.
Jatmiko Udik, Pribadiyono, Suhermin
doaj   +1 more source

Effect of Different Packaging Atmosphere on Microbiological Shelf Life, Physicochemical Attributes, and Sensory Characteristics of Chilled Poultry Fillets

Food Science of Animal Resources, 2022
This trial was conducted to evaluate the effect of overwrap, vacuum, and modified atmosphere packaging (MAP) on poultry breast fillets' microbiological, biochemical shelf life and sensory attributes.
Kashif Nauman, Muhammad Hayat Jaspal, Bilal Asghar, Adeel Manzoor, Kumayl Hassan Akhtar, Usman Ali, Sher Ali, Jamal Nasir, Muhammad Sohaib, Iftikhar Hussain Badar   +9 more
doaj   +1 more source

The Coevolution of Colour Patterns and Hindwing Shapes on a Large Phylogenetic Scale Reveals Predation‐Driven Adaptive Syndromes in Swallowtail Butterflies

Ecology Letters, Volume 29, Issue 1, January 2026.
By combining computer vision and morphometrics on museum specimens, we show that hindwing tail shape and colour patterns evolved in concert across swallowtails. Long‐tailed species display contrasted stripes and marginal spots, suggesting coevolution of deflective traits promoted by natural selection by predators.
Agathe Puissant, Ariane Chotard, Fabien L. Condamine, Vincent Debat, Violaine Llaurens   +4 more
wiley   +1 more source

Web-Based Psychotherapy for Posttraumatic Stress Disorder in War-Traumatized Arab Patients: Randomized Controlled Trial

Journal of Medical Internet Research, 2015
BackgroundIn recent years, armed conflicts in the Middle East have resulted in high rates of exposure to traumatic events. Despite the increasing demand of mental health care provision, ongoing violence limits conventional approaches of mental health ...
Knaevelsrud, Christine, Brand, Janine, Lange, Alfred, Ruwaard, Jeroen, Wagner, Birgit   +4 more
doaj   +1 more source

Calcium‐dependent cooperativity and stability of Titin's tandem I82‐I83 domains

Protein Science, Volume 34, Issue 12, December 2025.
Abstract The muscle protein titin spans half a sarcomere, from M‐line to Z‐disk, and is essential for both active and passive stretch. The N2A region of titin plays a critical role in various regulatory processes through its binding interactions. Located at the C‐terminus of the N2A region, adjacent to the PEVK region, are the I82 and I83 domains ...
Colleen M. Kelly, Janette Jerusal, Mark Pfuhl, Matthew J. Gage   +3 more
wiley   +1 more source

Comparing the Efficacy of a Mobile Phone-Based Blood Glucose Management System With Standard Clinic Care in Women With Gestational Diabetes: Randomized Controlled Trial

JMIR mHealth and uHealth, 2018
BackgroundTreatment of hyperglycemia in women with gestational diabetes mellitus (GDM) is associated with improved maternal and neonatal outcomes and requires intensive clinical input. This is currently achieved by hospital clinic attendance every 2 to 4
Mackillop, Lucy, Hirst, Jane Elizabeth, Bartlett, Katy Jane, Birks, Jacqueline Susan, Clifton, Lei, Farmer, Andrew J, Gibson, Oliver, Kenworthy, Yvonne, Levy, Jonathan Cummings, Loerup, Lise, Rivero-Arias, Oliver, Ming, Wai-Kit, Velardo, Carmelo, Tarassenko, Lionel   +13 more
doaj   +1 more source