Results 101 to 110 of about 3,699,727 (297)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

MODELLING AND FORECASTING OF CLOUD DATA WAREHOUSING LOAD [PDF]

open access: yesApplied Computer Science, 2014
Cloud data storages in their internal structure are not using their full potential functionality because of the complexity of behavior of network traffic, which affects the quality of service.
Rostyslav STRUBYTSKYI
doaj  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Su alcune strutture di spazio metrico con sostegno‘…l'insieme delle variabili casuali associate a successioni di numeri a caso

open access: yesRatio Mathematica, 1993
Sommario: Si mostra come. generalizzando i concerti relativi all'analisi di Fourier di successioni di numeri pseudocasuali ed introducendo la nozione di variabile casuale n-dimensionale associata ad una successione di numeri pseudocasuali, si può dotare ...
Antonio Maturo
doaj  

Anna E. Broomall Club meeting minutes

open access: yes, 1919
Minutes of the Anna E. Broomall Club. Missionary Work and Public Health: see "In Memory of Dr.
Anna E. Broomall Medical Club
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

La coarticolazione e il VOT nello sviluppo fonetico: studio sperimentale su bambini dai 42 ai 47 mesi d’età.

open access: yes, 2013
Nelle prime tappe dello sviluppo linguistico, l’aspetto relativo all’acquisizione del correttocontrollo motorio pone al bambino una sfida altrettanto complessa e impegnativadell’acquisizione delle categorie cognitive relative alla produzione fonologica e,
Bortone E.   +3 more
core  

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