Results 191 to 200 of about 2,187,829 (266)

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Efficacy of psychosensory interventions for the management of pediatric pain, fear, and distress during emergency care: a systematic review and meta-analysis of randomized clinical trials. [PDF]

Front Pediatr
Bustamante Fernández M, Caes L, Rossel JI, Díaz Díaz G, Ruiz Valenzuela G, Caroca Madariaga S, Klein Vallecillo N, Hidalgo Vilche S, Tapia Espinoza V, González Zamarin M, Strasser K.   +10 more
europepmc   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

A 58-Year-Old Woman's Odyssey With Bilateral Nodular Opacities Comes to a Diagnosis. [PDF]

Cureus
Miziou A, Ntiloudis R, Kousidis P, Nikolaidou A, Gourgoulianis KI, Perlepe G.   +5 more
europepmc   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

Peroral cholangiopancreatoscopy-guided diagnosis and treatment of an intramural bile duct stone complicated with immunoglobulin G4-related cholangitis: a case report with video. [PDF]

Endoscopy
Wen S, Long H, Wang P, Yang W, Ren Y, Yang B, Guo M.   +6 more
europepmc   +1 more source

Elongated flap combined with pulley-traction method for the treatment of early duodenal bulb adenocarcinoma. [PDF]

Endoscopy
Wang Q, Ji R.
europepmc   +1 more source

Surficial geology, western Devon Island, Nunavut, NTS 58-H and parts of 58-E, F, G

, 2018
openaire   +1 more source

Integration and benefits of root inoculation with endophytic entomopathogenic fungus <i>Metarhizium brunneum</i> in the propagation of olive tree seedlings in nurseries. [PDF]

Appl Environ Microbiol
Romero-Conde A, Yousef-Yousef M, Valverde-García P, Sandoval-Lozano A, Quesada-Moraga E, Garrido-Jurado I.   +5 more
europepmc   +1 more source