Results 251 to 260 of about 182,417 (295)

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex   +4 more
wiley   +1 more source

Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro

open access: yesAdvanced Healthcare Materials, EarlyView.
A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski   +3 more
wiley   +1 more source

Peptide Display Directed Assembly of Biopolymer Core–Silica Shell Particles

open access: yesAdvanced Healthcare Materials, EarlyView.
Bacterial cells are engineered to produce biopolyester particles displaying peptides mediating growth of silica. Peptide‐coated biopolyester particles are treated with silica precursors and silica shell formation is studied. Transmission electron microscopy shows silica‐coated BPs which are formed after the silicification treatment. Characterization of
Deeptee Chandrashekhar Pande   +2 more
wiley   +1 more source

A Deployable 4D Printed, Mucoadhesive and Magnetically Guided Patch for Local Therapy of Gastric Cancer

open access: yesAdvanced Healthcare Materials, EarlyView.
A new perspective for treatment of gastric cancer is proposed utilizing 4D printing to develop shape morphing, deployable, and magnetically guided local drug releasing patches. The deployed patches are envisioned to adhere at the tumor site to locally deliver high drug amounts.
Dina B. Mahmoud   +3 more
wiley   +1 more source

Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction

open access: yesAdvanced Healthcare Materials, EarlyView.
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li   +7 more
wiley   +1 more source

Tracheal and cloacal bacterial diversity of red listed Eastern Imperial Eagle (<i>Aquila heliaca</i>). [PDF]

open access: yesFront Microbiol
Murtskhvaladze M   +8 more
europepmc   +1 more source

Biphasic Granular Bioinks for Biofabrication of High Cell Density Constructs for Dermal Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a biphasic granular bioink (µInk) that enables 3D bioprinting of high cell density constructs for dermal regeneration. The bioink promotes cell proliferation, ECM deposition, and neovascularization, leading to tissue integration and reduced scar formation in vivo.
Rozalin Shamasha   +16 more
wiley   +1 more source

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