Results 81 to 90 of about 20,978 (263)

How Digital Transformation affects Enterprise Architecture Management – a case study

International Journal of Information Systems and Project Management, 2022
Internet of Things (IoT), machine learning, cyber-physical systems and other recent technological innovations offer new opportunities for enterprises in the context of Digital Transformation (DT) but also cause new challenges for Enterprise Architecture
Kaidalova Julia, Sandkuhl Kurt, Seigerroth Ulf   +2 more
doaj  

The Impact of a Visualized Steerable Sheath on Radiofrequency Catheter Ablation for First-Time Atrial Fibrillation Ablation: A Prospective, Randomized, Single-Blind Study. [PDF]

Catheter Cardiovasc Interv
ABSTRACT Background A 3D electroanatomical mapping (3D‐EAM) visualized steerable sheath was designed to improve catheter placement and reduce radiation exposure during ablation, an established treatment for atrial fibrillation (AF). However, prospective randomized data comparing the procedural and clinical outcomes of visualized and non‐visualized ...
Chen CK, Yu CC, Liao MT, Huang HC, Liu YB.   +4 more
europepmc   +2 more sources

Newly identified human aminoacyl‐tRNA synthetase complex interacting multifunctional protein 2 (AIMP2) loss‐of‐function mutations cause neurodevelopmental defects linked to cell death in a zebrafish model

The FEBS Journal, EarlyView.
Human AIMP2 mutations lead to severe neurodevelopmental defects and brain atrophy. Using patient‐derived fibroblasts from two individuals, we show decreased AIMP2 protein levels and overall protein synthesis. In a zebrafish loss‐of‐function model, the lack of AIMP2 leads to an increase in cell death and results in smaller brains.
Patrick Mullen, Shenela Lakhani, Joshua Appelbaum, DéJenaé See, Pryce Patterson, Collin M. MacLeod, Alexandra George, Reza Maroofian, Margaret E. Ross, Christopher Francklyn, Alicia M. Ebert   +10 more
wiley   +1 more source

An Attachment and Multi‐Target Perspective on Organisational Commitment of Early Career Starters

International Journal of Training and Development, EarlyView.
ABSTRACT Establishing strong organisational commitment among early career starters such as apprentices, trainees, and dual‐study students is of central interest to companies' HR strategies for developing and retaining skilled workforces. To explain how commitment emerges, attachment theory offers a useful conceptual lens, as it provides an established ...
Jutta Bloem, Tammo Straatmann, Anna Maria Engel   +2 more
wiley   +1 more source

NLRP3 inflammasome regulates Th17/Treg cell balance in experimental autoimmune myocarditis

Biochemistry and Biophysics Reports
Objective: This study aimed to investigate whether the NLRP3 inflammasome modulates the Th17/Treg cell balance in experimental autoimmune myocarditis (EAM).
Lijun Su, Nan Qu, Lili Chen, Yuying Lin, Huiwen Mo, Yanlan Huang   +5 more
doaj   +1 more source

Prevalência e características dos eventos adversos a medicamentos no Brasil

Cadernos de Saúde Pública, 2018
Resumo: O presente trabalho tem como objetivo descrever a prevalência e fatores associados a eventos adversos a medicamentos (EAM) referidos por usuários de medicamentos no Brasil.
Livia Alves Oliveira de Sousa, Marta Maria de França Fonteles, Mirian Parente Monteiro, Sotero Serrate Mengue, Andréa Dâmaso Bertoldi, Tatiane da Silva Dal Pizzol, Noemia Urruth Leão Tavares, Maria Auxiliadora Oliveira, Vera Lucia Luiza, Luiz Roberto Ramos, Mareni Rocha Farias, Paulo Sergio Dourado Arrais   +11 more
doaj   +1 more source

Catheter Ablation: Evolution and Efficiencies

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT The present review includes a discussion the goals and pitfalls of efficiency in the medical profession, a historical perspective on the evolution of catheter ablation in the field of electrophysiology (EP), and the data regarding the relationship between efficiency and outcomes in the EP lab. Focus on efficacy is critical to maximize resource
Aravind G. Kalluri, Bradley P. Knight
wiley   +1 more source

Symbiose zwischen EAM und SOA [PDF]

, 2010
Serviceorientierte Architekturen (SOA) und Enterprise Architecture Management (EAM) werden häufig isoliert voneinander betrachtet. Serviceorientierung kann jedoch nur über eine Kombination von beidem effektiv umgesetzt werden.
Hanschke, Inge
core   +1 more source

Activation of ETAR and ETBR in myocardial tissue characterizes heart failure induced by experimental autoimmune myocarditis

BMC Cardiovascular Disorders
Background Endothelial dysfunction is characterized by an imbalance between endothelium-derived vasodilatory and vasoconstrictive effects and may play an important role in the development of heart failure.
Peng Yang, Yujing Wu, Fangfei Li, Jiangfeng Tang, Zhenzhong Zheng, Qingshan Tian   +5 more
doaj   +1 more source

Clinical Outcomes After Catheter Ablation in Patients With Structural Heart Disease and Ventricular Fibrillation

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction In patients with ischemic cardiomyopathy (ICM), recurrent VF may be treated with catheter ablation by targeting triggering premature ventricular complexes (PVCs) and/or ventricular scar homogenization. Data on optimal ablation strategies in patients with non‐ischemic cardiomyopathy (NICM) remain limited.
Kenji Hashimoto, Samual Turnbull, Saurabh Kumar   +2 more
wiley   +1 more source