Results 101 to 110 of about 2,289,707 (361)

High-Speed Holographic Shape and Full-Field Displacement Measurements of the Tympanic Membrane in Normal and Experimentally Simulated Pathological Ears

open access: yesApplied Sciences, 2019
To improve the understanding of the middle-ear hearing mechanism and assist in the diagnosis of middle-ear diseases, we are developing a high-speed digital holographic (HDH) system to measure the shape and acoustically-induced transient displacements of ...
Haimi Tang   +7 more
doaj   +1 more source

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang   +12 more
wiley   +1 more source

An Ameloblastoma in the Middle Ear

open access: yesThe Journal of International Advanced Otology, 2019
Abstract   An ameloblastoma is a locally aggressive odontogenic tumour that commonly develops from the odontogenic epithelium within the jawbone. Here we present for the first time a case of a rare primary ameloblastoma in the middle ear cavity, along with some consideration of its treatment and a new classification.
Takashi Yamatodani   +5 more
openaire   +3 more sources

Effects of negative middle ear pressure on distortion product otoacoustic emissions and application of a compensation procedure in humans

open access: yes, 2009
Click on the DOI link below to access the article (may not be free).This study was intended to systematically examine the effect of negative middle ear pressure (MEP) on distortion product otoacoustic emissions (DPOAEs) and to validate a compensation ...
Sun, Xiao-Ming, Shaver, Mark D.
core   +1 more source

Systematic Review of Endoscopic Middle Ear Surgery Outcomes

open access: yesThe Laryngoscope, 2014
Middle ear surgery increasingly employs endoscopes as an adjunct to or replacement for the operative microscope. We provide a systematic review of endoscope applications in middle ear surgery with an emphasis on outcomes, including the need for ...
E. Kozin   +7 more
semanticscholar   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

open access: yesAdvanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang   +10 more
wiley   +1 more source

The Association of Outer Ear Commensal Bacteria with Otitis Media in Children

open access: yes, 2012
Background: Middle ear infections (otitis media) are a significant burden on children’s health. They are one of the more common childhood ailments and are responsible for about a third of children’s general practitioner visits.
White, Rebecca Katharine
core  

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

open access: yesAdvanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee   +11 more
wiley   +1 more source

Bone conduction and bone anchored hearing devices

open access: yes, 2003
This work aims to facilitate the exchange of ideas between otosurgeons and engineers on common topics such as middle ear function, tympanoplasty, implantable hearing devices and ear prostheses.
Stenfelt, Stefan, Stenfelt, Stefan,
core   +1 more source

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