Results 241 to 250 of about 762,616 (316)

A novel carcinogenic mouse model by site‐directed insertion of tandem human HRAS large DNA fragment into 15E1 site

Animal Models and Experimental Medicine, EarlyView.
The NF‐hHRAS mouse model was generated through Chr15 E1 locus‐targeted integration of a 21 kb multicopy HRAS gene cluster. The NF‐hHRAS model demostrated tissue‐specific expression of human HRAS across multiple organs and low spontaneous tumorigenesis.
Susu Liu, Yanwei Yang, Guitao Huo, Hao Yang Zhao, Chen Ling, YuYa Wang, Shijie Zhai, Xiaowei Sun, Wenda Gu, Yuan Cao, Wei Gong, Sanlong Wang, Changfa Fan   +12 more
wiley   +1 more source

A Critique of the Stenger Test. [PDF]

Audiol Res
Bell A, Westcott M, Jedrzejczak WW.
europepmc   +1 more source

An in vivo assay for osteoclast activity using mouse calvaria

Animal Models and Experimental Medicine, EarlyView.
This study describes a novel method for measuring osteoclast‐mediated bone resorption in vivo using a mouse model. Localized injection of RANKL in a basement membrane matrix above the cranium induced osteoclast‐mediated bone resorption. Utilizing micro‐computed tomography and a semiautomated three‐dimensional analysis program, osteoclast resorption pit
Christopher Grieg, Maya Deza Culbertson, J. Patrick O'Connor   +2 more
wiley   +1 more source

Mucoadhesive polydopamine-coated nanoparticle-mediated inner ear drug delivery for hearing loss treatment. [PDF]

J Transl Med
Kim S, Cheon SY, Yang KJ, Won SS, Chun S, Nam H, Kim DK, Koo H.   +7 more
europepmc   +1 more source

STING deficiency promotes motor recovery in mice following brachial plexus root avulsion

Animal Models and Experimental Medicine, EarlyView.
STING deficiency can increase the body weight, promote motor recovery, decrease MN death, inhibit pyroptosis and neuroinflammation, increase remyelination, and reduce the atrophy of the biceps brachii in mice with BPRA. Abstract Background Brachial plexus root avulsion (BPRA), a well‐known form of peripheral nerve injury, results in motor function loss
Yu Peng, Ying Zhang, Shenhui Yang, Lu He, Shuangxi Chen   +4 more
wiley   +1 more source

Conductive hearing loss from ossicular compression by aberrant vessel. [PDF]

J Surg Case Rep
Almutairi HM, Alanazi NF, Alboqamie AF, Alalayat L.   +3 more
europepmc   +1 more source

A novel inhaled anesthesia technique for concurrent direct laryngoscopy in rats

Animal Models and Experimental Medicine, EarlyView.
Our novel nose cone anesthetic technique allows the use of gas anesthesia during concurrent direct laryngoscopy. Inhaled anesthesia not only has a better safety profile for rats, but also increases lab efficiency when compared to injectable anesthesia. Abstract The current anesthetic standard for laryngoscopy in rats utilizes injectable intraperitoneal
Corinne Negvesky, Amin Mirzaaghasi, Eric M. Smith, Ashley E. Kita   +3 more
wiley   +1 more source

Temporal Bone Carcinoma Masquerading as Complicated Chronic Otitis Media. [PDF]

Clin Case Rep
Shrestha SR, Malhotra M, Bhardwaj A, Suji PS, Khan SA.   +4 more
europepmc   +1 more source

Behavior Decoding Delineates Seizure Microfeatures and Associated Sudden Death Risks in Mouse Models of Epilepsy

Annals of Neurology, EarlyView.
Objective Behavior and motor manifestations are distinctive yet often overlooked features of epileptic seizures. Seizures can result in transient disruptions in motor control, often organized into specific behavioral sequences that can inform seizure types, onset zones, and outcomes.
Yuyan Shen, Jaden Thomas, Xianhui Chen, Jaden Zelidon, Mariam Najeeb, Abigayle Hahn, Ping Zhang, Aaron Sathyanesan, Bin Gu   +8 more
wiley   +1 more source

Evaluating Middle Ear Absorbance and Resonant Frequency in Patulous Eustachian Tube Patients Using Wideband Tympanometry. [PDF]

Otol Neurotol Open
Kusaka I, Ikeda R, Suzuki M, Onodera D, Katsura A, Suzuki J, Shiga K.   +6 more
europepmc   +1 more source