Results 121 to 130 of about 551,383 (311)

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

open access: yesAdvanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang   +6 more
wiley   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

open access: yesAdvanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung   +7 more
wiley   +1 more source

Novel Finite Element Method to Predict Blast Wave Transmission Through Human Ear [PDF]

open access: yes, 2016
As military weapons systems continue to become more powerful, the noise levels they generate become more dangerous to the soldiers deploying them. This has increased the need for advanced methods of evaluating the risks of weapon-generated pressure ...
Leckness, Kegan
core  

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

open access: yesAdvanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li   +5 more
wiley   +1 more source

The Association of Outer Ear Commensal Bacteria with Otitis Media in Children

open access: yes, 2012
Background: Middle ear infections (otitis media) are a significant burden on children’s health. They are one of the more common childhood ailments and are responsible for about a third of children’s general practitioner visits.
White, Rebecca Katharine
core  

Bone Conduction and the Middle Ear

open access: yes, 2012
With more than a century of research in the field of bone conduction (BC) hearing, the importance of the contributors for bone-conducted sound is not clarified and there is no consensus on the issues.
Stenfelt, Stefan,, Stefan Stenfelt
core   +1 more source

Full‐Stack Architectures for Intelligent Brain‐Computer Interfaces

open access: yesAdvanced Science, EarlyView.
System‐level overview of brain–computer interfaces (BCIs), illustrating the integration of neural signal acquisition, wireless transmission, and adaptive decoding. Advanced electrode, tissue interfaces, energy‐efficient communication, and robust algorithms collectively enable stable signal quality, real‐time processing, and closed‐loop operation ...
Hee Kyu Lee   +9 more
wiley   +1 more source

Test-retest reliability of real ear measurements for open canal hearing aid fittings

open access: yes, 2010
When fitting hearing aids with conventional earmoulds using real ear measurements (REM) it is recommended to use the modified pressure with concurrent equalization method whereby a reference microphone is used to monitor the REM loudspeaker output level.
Alaqrabawi, Wala'
core  

Is virtual endoscopy of the middle ear useful?

open access: yes, 2011
Virtual endoscopy is a relatively new imaging technology in otology, and therefore data on its efficacy in clinical situations are limited. We conducted a prospective study to evaluate the clinical relevance of radiologic diagnoses based on virtual ...
Au Yeung, KM   +4 more
core   +1 more source

Smart Denture with Embedded Thin‐Film Temperature Sensors Patterned by Femtosecond Laser Pulse for Elderly Healthcare

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
We demonstrate the direct‐laser patterning of a gold thin film on polymethyl methacrylate to fabricate a temperature sensor for dentures. The temperature sensor‐embedded smart dentures are evaluated in an oral environment, enabling in‐situ monitoring for elderly healthcare.
Han Ku Nam   +7 more
wiley   +1 more source

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