Results 111 to 120 of about 7,001 (225)

A Novel Decellularized Fibrocartilage Graft Promotes Tympanic Membrane Repair

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 29, 7 August 2026.
An off‐the‐shelf decellularized porcine meniscus fibrocartilage graft (MEND) is engineered for pediatric tympanoplasty. Featuring a microchannel architecture that promotes host cell invasion, MEND rapidly closes tympanic membrane perforations and fully remodels in vivo, outperforming fascia and matching cartilage grafts while avoiding donor‐site ...
Paul M. Gehret   +6 more
wiley   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 30, 14 August 2026.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano   +11 more
wiley   +1 more source

Alpha‐Mannosidosis in a 3.5‐Year‐Old Girl: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Alpha‐mannosidosis is a rare lysosomal storage disease caused by a deficiency of the enzyme alpha‐mannosidase. It manifests as a continuous spectrum of signs and symptoms characterized by dysmorphic features, skeletal abnormalities, delayed psychomotor and speech development, impaired hearing, and psychiatric involvement. When suspected, alpha‐
Samuel Bonilla Fornes   +4 more
wiley   +1 more source

Endoscopic Management of a Rare Pediatric Fronto‐Ethmoidal Mucocele With Orbital Involvement: Navigating Surgical Challenges

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Paranasal mucoceles are benign lesions causing bone erosion with orbital and intracranial extension. An 11‐year‐old male presented with right orbital proptosis with restricted movement. Computed tomography and Magnetic Resonance Imaging revealed a fronto‐ethmoidal mucocele involving orbit.
Sushil Raj Shrestha   +8 more
wiley   +1 more source

Neuromodulation Techniques in Chronic Cerebral Hypoperfusion: Mechanisms and Therapeutic Advances

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
Chronic cerebral hypoperfusion drives vascular cognitive impairment through neurovascular dysfunction, white matter injury, neuroinflammation, oxidative stress and synaptic network failure. Neuromodulation may offer a multi‐target strategy to restore plasticity, improve functional connectivity and support cognitive recovery. ABSTRACT Background Chronic
Chenye Qiao   +7 more
wiley   +1 more source

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