Frontiers in Bioengineering and Biotechnology, 2021 The rapid development of tissue engineering and regenerative medicine has introduced a new strategy for ear reconstruction, successfully regenerating human-ear-shaped cartilage and achieving the first clinical breakthrough using a polyglycolic acid ...
Litao Jia +13 more
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Intra-individual comparison of human ankle and knee chondrocytes in vitro: relevance for talar cartilage repair [PDF]
, 2009 OBJECTIVE: As compared to knee chondrocytes (KC), talar chondrocytes (TC) have superior synthetic activity and increased resistance to catabolic stimuli. We investigated whether these properties are maintained after TC are isolated and expanded in vitro.
Bonacina, E +20 more
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Fabrication of Stable Cartilage Framework for Microtia in Incomplete Synchondrosis [PDF]
Archives of Plastic Surgery, 2012 The synchondrosis between the sixth and seventh costal cartilage is usually used for the base frame in autogenous ear reconstruction. If the synchondrosis is loose, a variety of modifications can be devised.
Byung Chae Cho +4 more
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Response of human engineered cartilage based on articular or nasal chondrocytes to interleukin-1? and low oxygen [PDF]
, 2012 Previous studies showed that human nasal chondrocytes (HNC) exhibit higher proliferation and chondrogenic capacity as compared to human articular chondrocytes (HAC).
Sylvie Miot +20 more
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EBioMedicine, 2018 Microtia is a congenital external ear malformation that can seriously influence the psychological and physiological well-being of affected children. The successful regeneration of human ear-shaped cartilage using a tissue engineering approach in a nude ...
Guangdong Zhou +15 more
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Outcomes of Cartilage-Sparing Wide Local Excision for Primary Melanoma of the External Ear
OTO Open, 2020 Objective To describe outcomes after cartilage-sparing wide local excision for primary melanoma of the external ear. Study Design Retrospective analysis of patients undergoing external ear melanoma excision using a cartilage-sparing approach at a ...
Alisa Yamasaki MD +2 more
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Allogeneic Bone Marrow Transplant from MRL/MpJ Super-Healer Mice Does Not Improve Articular Cartilage Repair in the C57Bl/6 Strain. [PDF]
PLoS ONE, 2015 Articular cartilage has been the focus of multiple strategies to improve its regenerative/ repair capacity. The Murphy Roths Large (MRL/MpJ) "super-healer" mouse demonstrates an unusual enhanced regenerative capacity in many tissues and provides an ...
Catherine A Leonard +5 more
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Surgical concepts for reconstruction of the auricle [PDF]
, 1986 We compiled and evaluated the world literature on auricular reconstruction, for a total of over 400 publications, more than 200 authors, and over 3,300 reported cases. We found that partial reconstructions were already performed as early as 600 BC; total
Toplak, F., Berghaus, Alexander
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Magnetic resonance imaging of the ear for patient-specific reconstructive surgery. [PDF]
PLoS ONE, 2014 INTRODUCTION: Like a fingerprint, ear shape is a unique personal feature that should be reconstructed with a high fidelity during reconstructive surgery.
Luc Nimeskern +8 more
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Tenascin-C fragments are endogenous inducers of cartilage matrix degradation [PDF]
, 2011 Cartilage destruction is a hallmark of osteoarthritis (OA) and is characterized by increased protease activity resulting in the degradation of critical extracellular matrix (ECM) proteins essential for maintaining cartilage integrity.
Hermansson, M +12 more
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