Towards the Clinical Application of Gene Therapy for Genetic Inner Ear Diseases. [PDF]
J Clin Med, 2023 Hearing loss, the most common human sensory defect worldwide, is a major public health problem. About 70% of congenital forms and 25% of adult-onset forms of deafness are of genetic origin.
Lahlou G +4 more
europepmc +2 more sources
Application of Nanomedicine in Inner Ear Diseases. [PDF]
Front Bioeng Biotechnol, 2021 The treatment of inner ear disorders always remains a challenge for researchers. The presence of various physiological barriers, primarily the blood–labyrinth barrier (BLB), limits the accessibility of the inner ear and hinders the efficacy of various ...
Lin Q +7 more
europepmc +2 more sources
Nanomaterials for Inner Ear Diseases: Challenges, Limitations and Opportunities. [PDF]
Materials (Basel), 2022 The inner ear is located deep in the temporal bone and has a complex anatomy. It is difficult to observe and obtain pathological tissues directly. Therefore, the diagnosis and treatment of inner ear diseases have always been a major clinical problem. The
Li L, Luo J, Lin X, Tan J, Li P.
europepmc +2 more sources
An Assistive Role of a Machine Learning Network in Diagnosis of Middle Ear Diseases. [PDF]
J Clin Med, 2021 The present study aimed to develop a machine learning network to diagnose middle ear diseases with tympanic membrane images and to identify its assistive role in the diagnostic process.
Byun H +7 more
europepmc +2 more sources
Efficient and accurate identification of ear diseases using an ensemble deep learning model. [PDF]
Sci Rep, 2021 Early detection and appropriate medical treatment are of great use for ear disease. However, a new diagnostic strategy is necessary for the absence of experts and relatively low diagnostic accuracy, in which deep learning plays an important role.
Zeng X +11 more
europepmc +2 more sources
High Human Papillomavirus DNA loads in Inflammatory Middle Ear Diseases. [PDF]
Pathogens, 2020 Background. Previous studies reported human papillomaviruses (HPVs) in middle ear tumors, whereas these viruses have been poorly investigated in chronic inflammatory middle ear diseases.
Malagutti N +14 more
europepmc +2 more sources
Prevalence of ear diseases in dogs – a retrospective 5-year clinical study [PDF]
Bulgarian Journal of Veterinary Medicine, 2018 The purpose of the present study was to present the results from a retrospective study on the preva-lence of ear diseases among 5870 dogs referred for examination and treatment at the Small Animal Clinic at the Faculty of Veterinary Medicine, Stara ...
G. Terziev, I. Borissov
doaj +2 more sources
Nanomedicine for Inner Ear Diseases: A Review of Recent In Vivo Studies. [PDF]
Biomed Res Int, 2017 Nanoparticles are promising therapeutic options for inner ear disease. In this report, we review in vivo animal studies in the otologic field using nanoparticles over the past 5 years.
Kim DK.
europepmc +2 more sources
Ear diseases and factors associated with ear infections among the elderly attending hospital in Arar city, Northern Saudi Arabia. [PDF]
Electron Physician, 2017 Background Changes in the anatomical structures and function of the ear can result in ear diseases, and may affect all age groups including the elderly as a result of aging Objective To identify the frequency and types of ear diseases among the elderly ...
Alenezi NG +8 more
europepmc +2 more sources