Results 151 to 160 of about 9,706,348 (372)

Inner Ear Disease

open access: yes, 2006
Publisher Summary It is now evident that the inner ear is not an “immunologically privileged” site and may mount an immune response against both foreign and self-antigens. This chapter focuses on sensorineural hearing loss (SNHL). This has been described and termed in different ways: autoimmune SNHL, immunemediated inner ear disease (IMIED ...
LUNARDI, Claudio, PUCCETTI, Antonio
openaire   +3 more sources

Consequences and Mechanisms of Noise‐Induced Cochlear Synaptopathy and Hidden Hearing Loss, With Focuses on Signal Perception in Noise and Temporal Processing

open access: yesAdvanced Science, EarlyView.
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley   +1 more source

Cellular Differences in the Cochlea of CBA and B6 Mice May Underlie Their Difference in Susceptibility to Hearing Loss

open access: yesFrontiers in Cellular Neuroscience, 2019
Hearing is an extremely delicate sense that is particularly vulnerable to insults from environment, including drugs and noise. Unsurprisingly, mice of different genetic backgrounds show different susceptibility to hearing loss.
Huihui Liu   +20 more
doaj   +1 more source

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

open access: yesAdvanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du   +13 more
wiley   +1 more source

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

open access: yesAdvanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin   +21 more
wiley   +1 more source

Deep Learning Techniques for Ear Diseases Based on Segmentation of the Normal Tympanic Membrane. [PDF]

open access: yesClin Exp Otorhinolaryngol, 2023
Park YS   +4 more
europepmc   +1 more source

ACUTE OTITIS EXTERNA AS SEEN AT THE UNIVERSITY OF NIGERIA TEACHING HOSPITAL, ENUGU. [PDF]

open access: yes, 2013
Aim: is to evaluate clinical features of AOE diagnosed in and to update the previous study from our facility.Methods: A prospective, clinical and laboratory study in a tertiary health facilityResults: A total of 3793 consecutive patients that attended ...
Ezeanolue, Basil   +3 more
core   +1 more source

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

Color Dependence Analysis in a CNN-Based Computer-Aided Diagnosis System for Middle and External Ear Diseases. [PDF]

open access: yesDiagnostics (Basel), 2022
Viscaino M   +6 more
europepmc   +1 more source

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