Results 251 to 260 of about 491,700 (340)
Machine learning methods for predicting adverse drug events: A systematic review
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo +8 more
wiley +1 more source
The authors report the development of a controlled and scalable 3D co‐culture system combining hiPSC‐derived erythromyeloid progenitors and neurospheres within the Ambr® 250 Modular platform operated with a newly designed perfusion system. This model faithfully recapitulates early microglia–neural interactions, enabling progenitor integration ...
Catarina M. Gomes +4 more
wiley +1 more source
Ear and mastoid process-related hospital admissions in England and Wales: A descriptive ecological study. [PDF]
Alsairafi ZK +5 more
europepmc +1 more source
ABSTRACT Studies on cell cryopreservation have been limited by the complexity of the freezing process and challenges on controlling ice formation, managing cooling rates, and optimizing cryoprotectant concentrations. The objective of this study is to evaluate the impact of bottom‐up and conventional radial freezing on the viability of mammalian cells ...
Rafaela Ouro Neves +8 more
wiley +1 more source
Delivery strategies of messenger RNA therapeutics for brain disorders
Thus, mRNA therapeutics offer a powerful new avenue for the treatment of brain diseases. This review examines strategies to bypass biological barriers, particularly the blood–brain barrier, and explores emerging delivery systems, such as direct intracerebral injection, intracerebroventricular injection, systemic delivery (including intravenous ...
Kounghwa Youn +5 more
wiley +1 more source
Otitis media caused by <i>Vibrio cholerae</i> in a child: a case report and literature review. [PDF]
Venuti L +10 more
europepmc +1 more source

