Results 151 to 160 of about 39,759 (339)

Cause Specific Mortality in Japan: Contour Maps Approach [PDF]

open access: yes, 1986
An important part of the activity of IIASA's Population Program is related to the development of data visualization techniques. The paper is devoted to the analysis of cause specific mortality data for Japan using the shaded contour map approach which ...
Gambill, B.A.   +4 more
core  

Ipsilateral cochlear implantation in cases with vestibular schwannoma

open access: yesEye &ENT Research, EarlyView.
Abstract Background Vestibular schwannomas (VS) are the most common tumors in the cerebellopontine angle, which can lead to hearing loss, particularly following tumor resection. For patients with bilateral VS associated with neurofibromatosis type 2 (NF2), hearing loss significantly undermines their quality of life.
Qian Wan   +7 more
wiley   +1 more source

EZH2 negatively regulates IL‐8 expression in human nasal epithelial cells through its histone methyltransferase activity

open access: yesEye &ENT Research, EarlyView.
Abstract Background Chronic rhinosinusitis (CRS), characterized by persistent inflammation of the nasal and sinus mucosa, exhibits an escalating global prevalence and incidence. Interleukin‐8 (IL‐8), a key chemokine driving neutrophil recruitment, is implicated in CRS pathogenesis.
Yu Song   +4 more
wiley   +1 more source

Induction of mammary neoplasms in the ACI rat by 430-keV neutrons, X-rays, and diethylstilbestrol [PDF]

open access: yes, 1982
Chmelevsky, D.   +4 more
core   +1 more source

Targeting thymic stromal lymphopoietin in nasal type 2 inflammation

open access: yesEye &ENT Research, EarlyView.
Abstract Epithelial cell‐derived thymic stromal lymphopoietin (TSLP) plays a crucial role in mediating type 2 immune responses, which is one of the key underlying pathophysiological mechanisms of allergic rhinitis (AR) and most presentations of chronic rhinosinusitis with nasal polyps (CRSwNP).
Xintong Li   +3 more
wiley   +1 more source

Phenotype characterization of heart failure with preserved ejection fraction in medical device and surgical trials

open access: yesESC Heart Failure, EarlyView.
This systematic review identified 24 clinical trials of medical device and surgical interventions for HFpEF, with 16 demonstrating at least safety and feasibility, but little evidence of long‐term benefit. Phenotype‐based responses suggest that certain interventions may benefit specific HFpEF subgroups, yet most trials suffered from heterogeneous ...
Kurdo Araz   +5 more
wiley   +1 more source

Effectiveness and safety of early add‐on therapy with brivaracetam in patients with poorly controlled focal seizures in routine clinical practice: BRIV‐add study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To evaluate the effectiveness and safety of brivaracetam (BRV) as an add‐on therapy in patients with focal onset seizures who did not achieve seizure freedom with antiseizure medication (ASM) monotherapy in routine clinical practice.
Pedro J. Serrano‐Castro   +10 more
wiley   +1 more source

Teaching Students to Understand Knowledge: Stress‐Testing the ‘Justified True Belief Account’ for Critical Thinking

open access: yesFuture in Educational Research, EarlyView.
ABSTRACT This conceptual essay, grounded in a close reading of Plato's Theaetetus, argues that before educators can effectively operationalise critical thinking as the rigorous evaluation ('stress‐testing') of competing knowledge claims, university students must first understand foundational epistemological principles rooted in Plato's tripartite ...
Gerry Dunne
wiley   +1 more source

Anti‐Inflammatory Effects of Flavonoids in Otitis Media: A Systematic Review of Pre‐Clinical Evidence

open access: yesFood Frontiers, EarlyView.
Otitis media (OM) is a middle ear infection driven by chronic inflammation, leading to tissue damage and complications such as cholesteatoma. Flavonoids, a class of polyphenols with anti‐inflammatory properties, suppress key inflammatory mediators, reducing neutrophilic infiltration and mucosal thickening. These findings suggest flavonoids as potential
Madiha Ajaz   +3 more
wiley   +1 more source

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