Results 191 to 200 of about 658,233 (359)

Loss of the Y Chromosome in Oral Potentially Premalignant Disorders Predicts Malignant Progression: An Integrative Cross‐Species Multi‐Cohort Bioinformatic Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The loss of the Y chromosome (LOY) and the extreme down‐regulation of Y chromosome gene expression (EDY) are frequently observed in oral squamous cell carcinoma (OSCC). However, their roles in oral potentially malignant disorders (OPMDs) are unclear.
Rui Han   +6 more
wiley   +1 more source

Genomic and Immune Correlates of EZH2 Expression and Activity in Olfactory Neuroblastoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Purpose Olfactory neuroblastoma (ONB) is a rare sinonasal malignancy with limited therapeutic options in the recurrent/metastatic setting; little is known regarding its responsiveness to immunotherapy. Inhibition of enhancer of zeste homolog 2 (EZH2) has been shown to improve T‐cell‐mediated killing and susceptibility to immune checkpoint ...
Elisabetta Xue   +12 more
wiley   +1 more source

Neoadjuvant Immunotherapy for Periauricular Cutaneous Squamous Cell Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The standard‐of‐care for advanced periauricular cutaneous squamous cell carcinoma (pCSCC) is surgery and adjuvant radiation therapy. Neoadjuvant immunotherapy recently demonstrated high pathologic response rates in patients with resectable pCSCC.
David Z. Allen   +6 more
wiley   +1 more source

Evaluation of the Efficacy of Surgical Treatment of Middle Ear Paraganglioma. [PDF]

open access: yesClin Med Res
Abdrakhmanova D   +4 more
europepmc   +1 more source

Oncologic Safety of Facial‐Vessel–Based Buccinator Myomucosal Flaps for Tongue and Oral Floor Reconstruction: A Retrospective Multicenter Case–Control Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Buccinator myomucosal flaps (BMFs) have been proposed as a reconstructive solution for defects of the tongue and oral floor; however, their harvest requires preservation of the facial artery and vein. This study aimed to evaluate the oncologic safety of this approach compared with free fasciocutaneous flaps (FFF).
Luigi Angelo Vaira   +24 more
wiley   +1 more source

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