Results 161 to 170 of about 11,496,581 (289)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Identifying Prognostic Factors Implicated in Chronic Functional Abdominal Pain in Children: A Systematic Review. [PDF]

Gastroenterology Res
Richardson H, Bland R, Gray K.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Discovery of a star sensitive to the spin of Sagittarius A. [PDF]

Nature
Abd El Dayem K, Abuter R, Aimar N, Amaro-Seoane P, Berdeu A, Berger JP, Bourdarot G, Brandner W, Burkert A, Caldéron D, Correia C, Cuadra J, Davies R, Defrère D, Delit L, Drescher A, Eisenhauer F, Esteras Otal L, Fabricius M, Feuchtgruber H, Flesch S, Förster Schreiber NM, Foschi A, Fournier Q, Garcia P, Garcia Lopez R, Generozov A, Genzel R, Gillessen S, Gonté F, Haubois X, Hönig SF, Houllé M, Joharle S, Kaufer A, Kammerer J, Kervella P, Kolb J, Kreidberg L, Labadie L, Lacour S, Lai O, Laugier R, Le Bouquin JB, Leftley J, Li R, Lopez B, Lutz D, Mang F, Mérand A, Millour F, Montargès M, Morujão N, Nowacki H, Nowak M, Oberti S, Osorno J, Ott T, Paumard T, Paladini C, Pappert S, Perets HB, Perraut K, Perrin G, Petrov R, Petrucci PO, Piran T, Pourré N, Rabien S, Ribeiro DC, Robbe-Dubois S, Sadun Bordoni M, Sanchez-Bermudez J, Santos D, Sari R, Sauter J, Scheithauer S, Scigliuto J, Shangguan J, Shimizu TT, Soulez F, Stadler J, Straubmeier C, Sturm E, Subroweit M, Sykes C, Tacconi LJ, Thévenet P, Urso I, Vincent F, Woillez J, Zins G, GRAVITY+ Collaboration.   +92 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Properties of stable massive quark stars in holography. [PDF]

Eur Phys J C Part Fields
Bitaghsir Fadafan K, Cruz Rojas J, Mager J.   +2 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Anterior Mediastinal Mature Teratoma Presenting With Mediastinal Mass Syndrome in a Six-Month-Old Infant: Diagnostic Pitfalls and Anesthetic Challenges. [PDF]

Clin Case Rep
Khanbabaee GT, Shafiee A, Ghomi Z, Mahdavi NS, Mohajerzadeh L, Nilipour Y, Mahdavi SA.   +6 more
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Atmospheres of early type stars.

The Astronomical Journal, 1948
openaire   +2 more sources