Results 221 to 230 of about 40,670 (264)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Infrared Spectra of Early-Type Stars.

The Astrophysical Journal, 1947
openaire   +1 more source

Early-type emission-line stars

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Isophot Observations of Early-Type Stars

Astrophysics and Space Science, 1997
Mass loss has an important effect on the evolution of early-type stars. The most reliable mass loss rates are determined from the radio continuum. However there is a wealth of observational evidence (Discrete Absorption Components, X-rays, IR continuum, Hα variability, …) indicating that the stellar wind is clumped.
R. Blomme, M.C. Runacres, K. Vyverman, M. Cohen, C. Leitherer, S. P. Owocki, M. Haas   +6 more
openaire   +1 more source

Early type stars with abnormal spectra

Vistas in Astronomy, 1974
Abstract One of the areas which have received a great deal of attention in recent years is the field of the so-called early type peculiar stars. It seems that a review paper on the subject could be of some use, since it helps to visualize both the problems which have been solved and those which have not been solved or studied yet.
Mercedes Jaschek, Carlos Jaschek
openaire   +1 more source

Early-type Emission-line Stars

2007
Wolf-Rayet (WR) stars owe its name to the discoverers, C. Wolf and G. Rayet. They are one of the most conspicuous stellar objects in spectral features, activities, and in the processes of stellar evolution. They are spectroscopically characterized by the following features.
Tomokazu Kogure, Kam-Ching Leung
openaire   +1 more source