Results 121 to 130 of about 11,289,368 (310)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Relationship between blood malondialdehyde,endotoxin,MPV/PLT ratio and early kidney injury in patients with severe acute pancreatitis

open access: yesZhongguo linchuang yanjiu
Objective To investigate the relationship between serum malondialdehyde(MDA),endotoxin,peripheral blood mean platelet volume(MPV)to platelet count(PLT)ratio and early acute kidney injury in patients with severe acute pancreatitis(SAP),and to provide a ...
MA Bingbo,ZHU Changmiao,YOU Shaohan,LIU Pinhang
doaj   +1 more source

Oregon Early Childhood Inclusion indicators initiative annual report. Vietnamese

open access: yes, 2022
This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government ...

core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Oregon Early Childhood Inclusion indicators initiative annual report. Arabic

open access: yes, 2022
This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government ...

core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Comparison of Current International Guidelines on Premature Ejaculation: 2024 Update

open access: yesDiagnostics
Premature ejaculation (PE) is a common male sexual dysfunction that can cause significant distress in the patient and partner. This study aimed to compare the current international guidelines on PE to highlight their similarities and differences.
Lorenzo Romano   +14 more
doaj   +1 more source

Early learning program guidelines

open access: yes, 2009
[Rev. 2009].; Title from PDF cover (viewed on Apr. 26, 2010).; Includes bibliographical references (p. 51-54).All children are born ready to learn -- Environments matter -- Relationships are influential -- Communication is critical.Ohio's Early Learning ...

core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Early integration needs early education [PDF]

open access: yesPalliative Medicine, 2016
Frank, Elsner   +2 more
openaire   +2 more sources

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