Results 171 to 180 of about 611,410 (268)

Suicide mortality among adolescents and young adults aged 10-24 years in the Americas, 2000-2021: an analysis using the WHO Global Health Estimates. [PDF]

Lancet Reg Health Am
Nguyen N, Martinez R, Irarrazaval M, Oliveira E Souza R, Hennis AJM.   +4 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Parental income and drug use disorder among second-generation individuals in Sweden: effect modification by immigrant background and region of origin. [PDF]

BMC Public Health
Okuyama K, Lönn SL, Khoshnood AM, Assari S, Sundquist J, Sundquist K.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Evolution of Southern Hemisphere Westerly asymmetry since the Early Miocene. [PDF]

Sci Adv
Gai C, Struve T, Roberts AP, Li Y, Zhu C, Chen Y, Wei J, Liu W, Zhang W, Liu H, Wu H, Liu Q.   +11 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The evolutionary history and unique genetic diversity of Indigenous Americans. [PDF]

Nature
Castro E Silva MA, Nunes K, Ribeiro MR, Passarelli-Araujo H, Lemes RB, Kimura L, Sacuena P, G Amorim CE, Bortolini MC, Mill JG, Guerreiro JF, Barbieri C, Hernández-Zaragoza DI, Walter A, Chowdhury TN, Macías-Herrera D, Lara-Riegos JC, Del Castillo-Chávez O, Zurita C, Tito-Álvarez AM, Vásquez-Domínguez E, Moo-Mezeta ME, Torres-Romero JC, Aguilar-Campos A, Serrano-Osuna R, Parolín ML, Bravi CM, Ramallo V, Bailliet G, Revollo S, Sandoval JR, Fujita R, Barquera R, Santos FR, Comas D, Hünemeier T.   +35 more
europepmc   +1 more source