The impact of additive or substitutive clinical study design on the negotiated reimbursement for oncology pharmaceuticals after early benefit assessment in Germany [PDF]
Health Economics Review, 2020 Background We analysed the impact of clinical study design for oncological pharmaceuticals on the subsequent price negotiations after early benefit assessment between pharmaceutical companies and the German National Association of Statutory Health ...
C. M. Dintsios, I. Beinhauer
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Patient-reported data informing early benefit assessment of rare diseases in Germany: A systematic review [PDF]
Health Economics Review, 2019 Background Since the implementation of the Regulation on Patient Integration (2003), the Act on the Reorganization of the Pharmaceutical Market (2011), and the Patient Rights Law (2013), the inclusion of patient perspectives has been further anchored in ...
Ana Babac +2 more
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Assessment of the Cost–Benefit Literature on Early Childhood Education for Vulnerable Children
SAGE Open, 2015 Given international interest in evidence-informed early education policy, we sought to interpret what is often a confusing literature on the performance of early childhood education programs.
Kim M. Dalziel +2 more
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Methodological approach to determine minor, considerable, and major treatment effects in the early benefit assessment of new drugs [PDF]
Biometrical Journal, 2016 Beate Wieseler
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Expanding the Role of Early Health Economic Modelling in Evaluation of Health Technologies; Comment on “Problems and Promises of Health Technologies: The Role of Early Health Economic Modeling” [PDF]
International Journal of Health Policy and Management, 2021 In this commentary, we discuss early stage assessments of innovative medical technologies both in terms of methods applied as well as their use in healthcare decision-making.
Carlo Federici, Aleksandra Torbica
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eLife, 2021 Tuberculous meningitis has high mortality, linked to excessive inflammation. However, adjunctive anti-inflammatory corticosteroids reduce mortality by only 30%, suggesting that inflammatory pathophysiology causes only a subset of deaths.
Laura Whitworth +12 more
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Deep Brain Stimulation in Early-Stage Parkinson’s Disease: Patient Experience after 11 Years
Brain Sciences, 2022 The deep brain stimulation (DBS) in early-stage Parkinson’s disease (PD) pilot trial began more than a decade ago and remains the only investigation of DBS in mildly symptomatic patients.
Kaitlyn Stoehr +5 more
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A benefit-cost analysis framework for prioritization of control programs for well-established invasive alien species [PDF]
NeoBiota, 2021 Invasive alien species (IAS) are identified as a major threat to biodiversity and ecosystem services. While early detection and control programs to avoid establishments of new alien species can be very cost-effective, control costs for well-established ...
Rakel Blaalid +3 more
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Global Energy Interconnection, 2020 Cross-border grid interconnection is a critical means to achieve wide-area share of hydro and other clean energy. Economic benefit assessment of cross-border grid interconnection projects should be carefully performed during early stage. In this paper, a
Caihao Liang +3 more
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Progress in Disaster Science, 2019 Samoa is extremely exposed to natural hazards, particularly tropical cyclones and earthquake-generated tsunami. Some studies have put forth the position that adequate investment in early warning systems can contribute to the social and economic well ...
Bapon S.H.M. Fakhruddin, Lauren Schick
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