An Early Bronze Age 'dagger grave' from Rameldry Farm, near Kingskettle, Fife [PDF]
In February 2000, ploughing disturbed the capstone of a cist, located on the side of a prominent knowe at Rameldry Farm, near Kingskettle in central Fife.
Baker, L, Cowie, Trevor, Sheridan, J A
core
A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis
Background Individuals with serum elevations of anti‐cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such ‘at‐risk’ individuals. However, hydroxychloroquine (HCQ) is used without supporting clinical trial evidence.
Kevin D. Deane +33 more
wiley +1 more source
Diagnostic Implications and Correlates of Plasma Adenosine Deaminase 2 Activity and ADA2 Variants
Objective Deficiency of adenosine deaminase 2 (DADA2) is a monogenic autoinflammatory disease manifested as polyarteritis nodosa, stroke, and bone marrow failure. Leveraging an international cohort of 200 DADA2 cases, we aimed to characterize the diagnostic utility of a plasma ADA2 enzyme activity assay and understand the implications of residual ADA2 ...
Jian Yue +55 more
wiley +1 more source
Dysregulation of U12‐Type Splicing in Lupus Neutrophils
Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco +11 more
wiley +1 more source
Atypical Visually Guided Precision Grip Control in Middle‐Aged and Older Autistic Adults
ABSTRACT Sensorimotor impairments are well documented in autism spectrum disorder (ASD). However, little is known about how these difficulties present in middle‐aged and older autistic adults or how they relate to demographic factors and autistic traits.
Zheng Wang +9 more
wiley +1 more source
ABSTRACT Preliminary studies suggest there are differences in the facial expressions produced by autistic and non‐autistic individuals. However, it is unclear what specifically is different, whether such differences remain after controlling for facial morphology and alexithymia, and whether production differences relate to perception differences ...
Connor T. Keating +3 more
wiley +1 more source
Child murder in the Early Bronze Age: proteomic sex identification of a cold case from Schleinbach, Austria. [PDF]
Rebay-Salisbury K +7 more
europepmc +1 more source
La Cueva Santa del Cabriel (Mira, Cuenca): Lugar de culto antiguo y ermita cristiana. Cueva Santa del Cabriel (Mira, Cuenca): Antique cult site and christian hermitage [PDF]
La Cueva Santa del Cabriel ofrece una larga ocupación que se extiende desde un momento avanzado del Calcolítico y el inicio de la Edad del Bronce hasta la actualidad.
Lorrio, Alberto J. +4 more
core +1 more source
5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng +14 more
wiley +1 more source
Abstract Private supplementary education is burgeoning worldwide, and over 25% of English children have received private tutoring. The neoliberalisation of education and parents' responsibilisation for children's attainment have driven market growth, but not all can afford to participate.
Sarah L. Holloway +2 more
wiley +1 more source

