Results 181 to 190 of about 23,513,968 (309)

Effectiveness of the Moments that Matter parenting programme on caregiving practices, family violence, mental health and early child development in Kenya: a cluster-randomised controlled trial. [PDF]

BMJ Glob Health
Jeong J, McCann JK, Hadd AR, Ochuka W, Ochieng M.   +4 more
europepmc   +1 more source

Trajectories of socioeconomic inequality in early child development: a cohort analysis. [PDF]

Int J Equity Health, 2022
Houweling TAJ, Oude Groeniger J, Jansen PW, van Lier P, Horoz N, Buil M, van Lenthe FJ.   +6 more
europepmc   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Early child development and its determinants among 6-month-old infants in Bench Sheko Zone, Southwest Ethiopia: a cross-sectional baseline analysis. [PDF]

BMC Public Health
Awoke SS, Debelew GT, Worku BN, Asres A.
europepmc   +1 more source

Formative research to inform the future design of a multicomponent fatherhood intervention to improve early child development in Mwanza, Tanzania. [PDF]

Soc Sci Med, 2023
Jeong J, McCann JK, Alsager A, Bhojani A, Andrew N, Joseph J, Ahun MN, Kabati M, Joachim D.   +8 more
europepmc   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Find your village: co-designing a community asset-based peer support intervention for wellbeing, social connectedness, and early child development among migrant families during the first 1001 days. [PDF]

Glob Health Action
Allport T, Musse S, Ingram J, Feder G, Osman F, Redwood S.   +5 more
europepmc   +1 more source

Editorial: Early child development in play and education: A cultural-historical paradigm. [PDF]

Front Psychol, 2022
Veraksa N, Pramling Samuelsson I, Colliver Y.   +2 more
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source