Results 131 to 140 of about 2,006,772 (358)

Childhood Poverty, Early Motherhood and Adult Social Exclusion [PDF]

open access: yes
Childhood poverty and early parenthood are both high on the political agenda. The key new issue addressed in this research is the relative importance of childhood poverty and of early motherhood as correlates of outcomes later in life.
John Hobcraft, Kathleen E Kiernan
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Hindrance stressors and turnover intentions among preschool teachers: The mediating role of work engagement and the moderating effect of meaningful work

open access: yesHeliyon
Background: Teacher turnover in preschool settings poses significant challenges to educational quality and stability. Understanding the factors that influence turnover intentions is crucial for developing effective retention strategies.
Jinghui Zhang, Yu Chen, Yige Xu, Yan Li
doaj   +1 more source

Impact of birthweight on health-care utilization during early childhood – a birth cohort study [PDF]

open access: gold, 2019
Mario Rüdiger   +5 more
openalex   +1 more source

Oral Health Intervention: A Multifaceted Approach to Improve Oral Health Care during Pregnancy [PDF]

open access: yes, 2016
Introduction: Early Childhood Caries (ECC) is the most common chronic disease of childhood Mothers’ oral health status is a strong predictor of the oral health status of their children 2009: Vermont spends $2.7 million treating children ages 0-5 with ...
Davis, Wendy   +7 more
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

The childhood development initiative: developing quality services [PDF]

open access: yes, 2008
The Childhood Development Initiative (CDI) has created a ten-year strategy to improve the health, safety and learning of the children of Tallaght West, and to strengthen their sense of belonging in their own communities.
French, Geraldine, Zappone, Katherine
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

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