Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
Unraveling the Early-Life Impacts of Environmental Exposures: From Fetal Growth to Child Development
ToxicsThe early-life period, encompassing fetal development, infancy, and early childhood, represents a window of extraordinary vulnerability to environmental influences [...]
Wei Xia
doaj +1 more source
DYNAMICS OF INDICATORS OF PHYSICAL AND PSYCHOPHYSIOLOGICAL DEVELOPMENT OF CHILDREN AGED 7 – 12
Вестник Кемеровского государственного университета, 2017 The article presents the results of the changes in the indices of physicaland psychophysiological development of children at the age of 7 – 12 years old with regard to gender.
N. G. Blinova +2 more
doaj +1 more source
Report on a special investigation of The Village Early Childhood Center (Center) located in Osceola, Iowa for the period January 1, 2013 through January 31, 2015. [PDF]
, 2017 Report on a special investigation of The Village Early Childhood Center (Center) located in Osceola, Iowa for the period January 1, 2013 through January 31 ...
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A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai +5 more
wiley +1 more source
Frontiers in EducationThe purpose of this study is to examine the mediating effect of teacher commitment on the relationship between burnout and role performance of early childhood teachers.
Sungwon Kim, Jiyoung Lee
doaj +1 more source
The Development of Early Childhood Education as an Academic Discipline in Finland
Nordisk Barnehageforskning, 2008 Early Childhood Education (ECE) as an academic discipline has gained an academic legitimacy in Finland in 2005. In accordance with internationally established practice, Early Childhood Education as an academic field and a field of research has been set ...
Eeva Hujala
doaj +1 more source
Stimulasi Sensorimotor Sebagai Layanan Holistik Integratif Unggulan di PAUD Terpadu Zaki’s Club Gemolong Kabupaten Sragen [PDF]
, 2016 The period of 5 (five) years of the life of the child is a 'golden period' (the golden period) or 'Window Opportunities' (window of opportunity) in laying the foundations of child development.
Rahayu, Sri
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Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Early-life medical care and human capital accumulation [PDF]
, 2015 Ample empirical evidence links adverse conditions during early childhood (the period from conception to age five) to worse health outcomes and lower academic achievement in adulthood. Can early-life medical care and public health interventions ameliorate
Daysal, N. Meltem
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