Results 221 to 230 of about 1,015,591 (337)

Double Thionation of 4‐Dimethylaminophthalimide Leads to the Development of a Highly Effective Photosensitizer

open access: yesChemistry – A European Journal, EarlyView.
We report on the photophysical properties and electronic relaxation mechanisms of 4‐dimethylaminophthalimide (DMAP) and thio‐4‐dimethylaminophthalimide (SDMAP). While DMAP is fluorescent, SDMAP shows negligible fluorescence due to ultrafast intersystem crossing to a long‐lived triplet state that decays in 3.4 ± 0.05 µs.
Chris Acquah   +8 more
wiley   +1 more source

A goodness‐of‐fit test for regression models with discrete outcomes

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract Regression models are often used to analyze discrete outcomes, but classical goodness‐of‐fit tests such as those based on the deviance or Pearson's statistic can be misleading or have little power in this context. To address this issue, we propose a new test, inspired by the work of Czado et al.
Lu Yang   +2 more
wiley   +1 more source

Synchronous Papillary Thyroid Microcarcinoma and Chronic Lymphocytic Leukemia: A Rare Interdisciplinary Case. [PDF]

open access: yesCureus
Farnin R   +7 more
europepmc   +1 more source

Prediction of Acute Liver Injury Trajectory in Patients Following Acetaminophen Overdose: A Multibiomarker Machine Learning Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries   +8 more
wiley   +1 more source

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara   +20 more
wiley   +1 more source

Metastatic high-grade undifferentiated ovarian carcinoma: A case report from Sub-Saharan Africa. [PDF]

open access: yesGynecol Oncol Rep
Lugata J   +8 more
europepmc   +1 more source

Conflict Management Strategies Among Cohabiting Undergraduate Students in Ilorin, Nigeria

open access: yesConflict Resolution Quarterly, EarlyView.
ABSTRACT Conflicts among cohabiting partners are often more complex or intractable because their relationships are not formalized culturally or institutionally. The inability to resolve conflicts among cohabiting partners may threaten their safety and well‐being.
Lanre Abdul‐Rasheed Sulaiman   +2 more
wiley   +1 more source

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