Results 1 to 10 of about 14,441,511 (335)
Communications Biology, 2021 Montoya Mira & Sapre et al. design a microfluidic device utilizing dielectrophoresis for the enrichment of circulating neoplastic cells that possess both epithelial and immune-like characteristics. They optimized the device using in vitro models and then
Jose Montoya Mira +9 more
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SAR-BagNet: An Ante-hoc Interpretable Recognition Model Based on Deep Network for SAR Image
Remote Sensing, 2022 Convolutional neural networks (CNNs) have been widely used in SAR image recognition and have achieved high recognition accuracy on some public datasets. However, due to the opacity of the decision-making mechanism, the reliability and credibility of CNNs
Peng Li +3 more
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Epigenetic loss of heterogeneity from low to high grade localized prostate tumours
Nature Communications, 2021 High tumour heterogeneity hinders the identification of molecular subtypes in prostate cancer. Here, the authors integrate single-cell chromatin accessibility data with multiplex imaging and reveal distinct chromatin features and transcriptional factor ...
Sebnem Ece Eksi +7 more
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Early detection: introduction [PDF]
European Respiratory Journal, 2003 The present Supplement of the European Respiratory Journal assembles a number of reviews on “Early detection” and it is the product of a symposium held in Barcelona on June 22 2002. The symposium was organised by the European Institute of Healthcare, which was set up by AstraZeneca.
M, Decramer, C, Roussos
openaire +2 more sources
Turning antibodies off and on again using a covalently tethered blocking peptide
Communications Biology, 2022 Modulation of antibody binding is developed through a photo-cleavable tether that is covalently conjugated to the antibody and to a blocking peptide.
Michael Brasino +7 more
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Selective enrichment of plasma cell-free messenger RNA in cancer-associated extracellular vesicles
Communications Biology, 2023 Extracellular vesicles (EVs) have been shown as key mediators of extracellular small RNA transport. However, carriers of cell-free messenger RNA (cf-mRNA) in human biofluids and their association with cancer remain poorly understood. Here, we performed a
Hyun Ji Kim +12 more
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Hybrid Silica-Coated PLGA Nanoparticles for Enhanced Enzyme-Based Therapeutics
Pharmaceutics, 2022 Some cancer cells rely heavily on non-essential biomolecules for survival, growth, and proliferation. Enzyme based therapeutics can eliminate these biomolecules, thus specifically targeting neoplastic cells; however, enzyme therapeutics are susceptible ...
Kyle T. Gustafson +8 more
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npj Precision Oncology, 2022 Cell-free RNA (cfRNA) in plasma reflects phenotypic alterations of both localized sites of cancer and the systemic host response. Here we report that cfRNA sequencing enables the discovery of messenger RNA (mRNA) biomarkers in plasma with the tissue of ...
Breeshey Roskams-Hieter +12 more
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The Egyptian Journal of Radiology and Nuclear Medicine, 2023 Background Aggressive invasion, high recurrence rate, and poor prognosis are common features of the human epidermal growth factor receptor-2 (HER2)-enriched breast cancer, yet on the other side, it shows significantly reduced activity in response to ...
Sahar Mansour +3 more
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Oncogene-mediated metabolic gene signature predicts breast cancer outcome
npj Breast Cancer, 2021 Breast cancer remains the second most lethal cancer among women in the United States and triple-negative breast cancer is the most aggressive subtype with limited treatment options.
Merve Aslan +13 more
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