Results 41 to 50 of about 1,564,555 (265)

Silent challenge: Early kidney transplant failure and cardiomyopathy

Clinical Case Reports, 2022
Differentiation of hypertrophic cardiomyopathy phenotypes is challenging but crucial for appropriate management. We report a case of myocardial oxalate deposition as an infrequent cause of infiltrative cardiomyopathy.
Raquel Santana‐Estupiñán, Francisco Valga, María del Val Groba Marco, Juan Carlos Quevedo‐Reina, David Bongiovanni, José Carlos Rodríguez‐Pérez   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Venous distensibility may be an indicator of early arteriovenous fistula failure, a retrospective single-centre cohort study

Renal Failure
Background Arteriovenous-fistula (AVF) are crucial for hemodialysis access, yet they frequently experience early failure. While studies have identified potential patient and clinical risk factors, these findings remain inconsistent.
Zead Tubail, Vincent Dinot, Christophe Goetz, Benjamin Savenkoff   +3 more
doaj   +1 more source

Early Warning Signs of Project Failure

MATEC Web of Conferences, 2018
Despite the improvement in utilization of project management tools and techniques over the years, there are still many projects failed to meet their objectives. Early warning signs becomes one of the concepts used to detect the potential cause of failure
Othman Idris, Ghani Siti Norfarahhanim, Mohamad Hisham, Alalou Wesam, Shafiq Nasir   +4 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Can We Predict Early Endoscopic Third Ventriculostomy Failure? The Role of Ultra-Early Postoperative Magnetic Resonance Imaging in Predicting Early Endoscopic Third Ventriculostomy Failure

World Neurosurgery: X, 2019
Background: The success of endoscopic third ventriculostomy (ETV) depends on multiple preoperative and intraoperative factors. The multifactorial influence adds an element of unpredictability to the outcome of the most well-planned procedure.
Suhas Udayakumaran, Ticini Joseph
doaj   +1 more source

Trisomy 1 in an early pregnancy failure

American Journal of Medical Genetics Part A, 2008
Trisomy 1 in an early pregnancy ...
Roje, Damir, Stipoljev, Feodora, Strinić, Tomislav, Mustapić, Ana   +3 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source