Results 241 to 250 of about 8,201,974 (327)

Earliest evidence of hominin bipedalism in <i>Sahelanthropus tchadensis</i>. [PDF]

Sci Adv
Williams SA, Wang X, Araiza I, Guerra JS, Meyer MR, Spear JK.   +5 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Managing Pulmonary Injury in Older Adults with Tuberculosis: The Role of Nursing Interventions. [PDF]

J Multidiscip Healthc
Zhang Q, Guo J, Lei H, Zhang Q.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Characterization of monogenic diabetes among Sudanese children: a multi-center experience from a population with high consanguinity. [PDF]

J Pediatr Endocrinol Metab
Hassan SS, Musa SA, De Franco E, Myers R, Van Heugten R, Babiker OO, Ibrahim AA, MohamadSalih GF, Ahmed A, Shatta JA, Al-Hassan OA, Patel KA, Abdullah MA.   +12 more
europepmc   +1 more source

Progress in homotransplantation of the liver. [PDF]

, 1966
Marchioro, TL, Porter, KA, Starzl, TE
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Genetic and epidemiological patterns of primary immunodeficiency diseases in Eastern Iranian patients. [PDF]

Sci Rep
Salehi M, Ahanchian H, Karimiani EG, Aelami MH, Moazzen N, Neshati Z, Pasdar A.   +6 more
europepmc   +1 more source

Medroxyprogesterone Acetate Inhibits Tumorigenesis in Mouse Models of Oviductal High-Grade Serous Carcinoma. [PDF]

Cancers (Basel)
Zhai Y, Bedi K, Wu R, Feng Y, Green ME, Pearce CL, Pike MC, Fearon ER, Cho KR.   +8 more
europepmc   +1 more source

Predicting electronic properties of molecules: a stacking ensemble model for HOMO and LUMO energy estimation. [PDF]

RSC Adv
Mahmoudi O, Kim MH.
europepmc   +1 more source