Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
A practical ECG-based model for early identification of acute heart failure following acute myocardial infarction. [PDF]
Guo X, Yan G, He H, Xu A, Zhan X, Gao G.
europepmc +1 more source
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Early Identification of Sepsis by Emergency Medical Services: Diagnostic Accuracy of Scoring Systems in a Retrospective Cohort. [PDF]
Kornfehl A +4 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Development and validation of a high-performance clinical predictive model for early identification of non-alcoholic fatty liver disease. [PDF]
Liang T, Ren J.
europepmc +1 more source
Smart IoT thermal imaging approach for early identification of Red Palm Weevil (RPW) infestation on palms. [PDF]
Martin B, Saranya S, Chowdary PJ.
europepmc +1 more source
Development and internal validation of a scoring model for early identification of ventricular arrhythmia risk in children with acute myocarditis. [PDF]
Li C, Wen T, Zhou Y, Lei C.
europepmc +1 more source
Artificial intelligence (AI) for early identification of radiotherapy related toxicities from the electronic health records of patients with head and neck cancer. [PDF]
Liu A +10 more
europepmc +1 more source

