Results 201 to 210 of about 3,388,275 (347)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Prevention and early intervention screening for inherited ocular diseases in Saudi Arabia: a national perspective. [PDF]

Front Ophthalmol (Lausanne)
AlEissa MM, Abedalthagafi M, Edward DP.
europepmc   +1 more source

Joint contractures in severe burn patients with early rehabilitation intervention in one of the largest burn intensive care unit in China: a descriptive analysis

, 2019
Jianglin Tan, Jian Chen, Junyi Zhou, Huapei Song, Huan Deng, Ming Ao, Gaoxing Luo, Jun Wu   +7 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Correction: Left ventricular function and coronary microcirculation in patients with mild reduced ejection fraction after STEMI

BMC Cardiovascular Disorders, 2022
Yuliang Ma, Lan Wang, Wenying Jin, Tiangang Zhu, Jian Liu, Hong Zhao, Jing Wang, Mingyu Lu, Chengfu Cao, Bailin Jiang   +9 more
doaj   +1 more source

Proposal for a new conceptual framework to guide early intervention professionals in a transcultural context. [PDF]

Front Public Health
Elias B, Bogossian A.
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Early Intervention as a Way of Reducing Neurocognitive Delay in Pediatric Sickle Cell Patients. [PDF]

Cureus
Wilson L, Riskin SI.
europepmc   +1 more source

Defying hard-to-heal wounds with an early antibiofilm intervention strategy: wound hygiene

, 2020
Christel Murphy, Leanne Atkin, Terry Swanson, Masahiro Tachi, Yih Kai Tan, Melina Vega de Céniga, Dot Weir, Randall D. Wolcott, Júlia Černohorská, Giorgio Ciprandi, Joachim Dissemond, Garth A. James, Jenny Hurlow, José Luis Lázaro‐Martínez, Beata Mrozikiewicz‐Rakowska, Pauline Wilson   +15 more
openalex   +2 more sources