Results 181 to 190 of about 895,320 (309)

Gut–Metabolome–Proteome Interactions in Age‐Related Hearing Loss: Insights from Fecal Microbiota Transplantation and Multi‐Omics Analyses

open access: yesAdvanced Science, EarlyView.
Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang   +12 more
wiley   +1 more source

Enhancing Cycling Stability of Aqueous Aluminum‐Metal Batteries via LaCl3‐Modulated Interfacial Reactions

open access: yesAdvanced Science, EarlyView.
In the aqueous AlCl3 electrolyte of aluminum‐metal batteries, the introduction of LaCl3 adjusts the solvation structure of Al3+ and enhances its diffusion level. The oxide precipitate formed by La3+ covers the aluminum metal anode and effectively alleviates corrosion reactions, thereby improving the cycling stability of the battery.
Yanshen Gao   +12 more
wiley   +1 more source

Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells

open access: yesAdvanced Science, EarlyView.
Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale   +6 more
wiley   +1 more source

Evaluation of iron accumulation during childhood cancer treatment. [PDF]

open access: yesFront Pediatr
Çalışkan Kamış Ş   +3 more
europepmc   +1 more source

Water‐Efficient Smart Drip Irrigation Enabled by a Low‐Power and High‐Efficiency Flexible Electromagnetic Actuator

open access: yesAdvanced Science, EarlyView.
Water scarcity poses a critical threat to global food security. A low‐power, flexible electromagnetic actuator is presented for smart drip irrigation systems. The device achieves precise, wide‐range flow modulation (0.05–5.8 mL/min) in response to real‐time plant demands, reducing water consumption compared to conventional flood irrigation.
Duo Chen   +7 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

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