Results 41 to 50 of about 898,797 (309)

New contributions for the early iron age stratigraphy at the site of Hisar in Leskovac (Sector I) [PDF]

Starinar, 2017
Archaeological research at the site of Hisar in Leskovac began more than a decade ago and has initiated numerous papers on the relationship between the Mediana and Brnjica cultural groups and cultures that marked the transition from the Bronze ...
Kapuran Aleksandar
doaj   +1 more source

High Redshift Quasars and Star Formation in the Early Universe

, 2001
In order to derive information on the star formation history in the early universe we observed 6 high-redshift (z=3.4) quasars in the near-infrared to measure the relative iron and \mgii emission strengths.
Dietrich M., Dietrich M., Guilloteau S., Guilloteau S., I. Appenzeller, M. Dietrich, M. Vestergaard, Matteucci F., Perryman M. A. C., S. J. Wagner, Storey P. J., Taniguchi Y.   +11 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Radiocarbon and stable isotope evidence of dietary change from the Mesolithic to the Middle Ages in the iron gates: New results from Lepenski Vir [PDF]

, 2004
A previous radiocarbon dating and stable isotope study of directly associated ungulate and human bone samples from Late Mesolithic burials at Schela Cladovei in Romania established that there is a freshwater reservoir effect of approximately 500 yr in ...
Bonsall, C., Cook, G.T., Hedges, R.E.M., Higham, T.F.G., Pickard, C., Radovanovic, I.   +5 more
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

New objects in old structures: The Iron Age hoard of the Palacio III megalithic funerary complex (Almadén de la Plata, Seville, Spain) [PDF]

, 2015
Cultural contact, exchange and interaction feature high in the list of challenging topics of current research on European Prehistory. Not far off is the issue of the changing role of monuments in the making and maintaining of key cultural devices such as
Forteza González, M, García Sanjuán, L, Hernández Arnedo, MJ, Hunt Ortiz, MA, Martinón-Torres, M, Murillo-Barroso, M, Wheatley, D   +6 more
core  

The Coming of Iron in a Comparative Perspective [PDF]

, 2016
The paper deals with the introduction of iron as a new raw material in the transition period between the outgoing Bronze Age and the Early Iron Age.
Bebermeier, Wiebke, Brumlich, Markolf, Cordani, Violetta, de Vincenzo, Salvatore, Eilbracht, Heidemarie, Klinger, Jörg, Knitter, Daniel, Lehnhardt, Enrico, Meyer, Michael, Schmid, Stephan G., Schütt, Brigitta, Thelemann, Michael, Wemhoff, Matthias   +12 more
core   +1 more source

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth, Mert Sisman, Jinwei Zhang, Hyeong‐geol Shin, Xu Li, Bela Turk, Ali Fatemi, Thanh Nguyen, Eric Mallack   +8 more
wiley   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source