Results 121 to 130 of about 20,037,007 (385)
A case for environmental statistics of early-life effects
Philosophical Transactions of the Royal Society of London. Biological Sciences, 2019 There is enduring debate over the question of which early-life effects are adaptive and which ones are not. Mathematical modelling shows that early-life effects can be adaptive in environments that have particular statistical properties, such as reliable
W. Frankenhuis +2 more
semanticscholar +1 more source
Early childhood and the life course [PDF]
What happens to children in the early years has consequences right through the course of their lives. There are many opportunities to intervene and make a difference to the lives of children and young people.
Centre for Community Child Health
core
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Low-temperature thermochronology and its geological significance in the central-northern section of the western margin of the Ordos Basin [PDF]
Solid EarthThe study of low-temperature thermochronology at plate edges provides favourable constraints for regional tectonic evolution and surface processes. Based on the existing thermochronological data of multiple cooling events since the Mesozoic era, we ...
G. Xing +11 more
doaj +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
BMC Evolutionary Biology, 2018 Background Our understanding of the ontogeny of Palaeozoic brachiopods has changed significantly during the last two decades. However, the micromorphic acrotretoids have received relatively little attention, resulting in a poor knowledge of their ...
Zhiliang Zhang +3 more
doaj +1 more source
How Prebiotic Chemistry and Early Life Chose Phosphate
Life, 2019 The very specific thermodynamic instability and kinetic stability of phosphate esters and anhydrides impart them invaluable properties in living organisms in which highly efficient enzyme catalysts compensate for their low intrinsic reactivity ...
Ziwei Liu, J. Rossi, R. Pascal
semanticscholar +1 more source
The effects of shocks in early life mortality on later life expectancy and mortality compression: A cohort analysis [PDF]
I study how shocks in cohort-level early life conditions, as represented by deviations from trend in mortality before age 5, affect later mortality. I use data for six European countries and find that shocks that increase infant mortality decrease later ...
Mikko Myrskylä
core
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source