Results 141 to 150 of about 19,801,094 (386)
A case for environmental statistics of early-life effects
Philosophical Transactions of the Royal Society of London. Biological Sciences, 2019 There is enduring debate over the question of which early-life effects are adaptive and which ones are not. Mathematical modelling shows that early-life effects can be adaptive in environments that have particular statistical properties, such as reliable
W. Frankenhuis +2 more
semanticscholar +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Communications BiologyThe notable disparity of animal body plans can be traced back to the morphological innovations during the Cambrian explosion and represented by a number of soft-bodied and skeletal fossils that provide a compelling narrative for animal evolution ...
Hao Yun +7 more
doaj +1 more source
The effects of shocks in early life mortality on later life expectancy and mortality compression: A cohort analysis [PDF]
I study how shocks in cohort-level early life conditions, as represented by deviations from trend in mortality before age 5, affect later mortality. I use data for six European countries and find that shocks that increase infant mortality decrease later ...
Mikko Myrskylä
core
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Early life stress in male mice induces superoxide production and endothelial dysfunction in adulthood [PDF]
, 2016 Dao H. Ho +5 more
openalex +1 more source
Childhood socioeconomic position and sex-specific trajectories of metabolic traits across early life: prospective cohort study [PDF]
, 2023 Kate O’Neill +9 more
openalex +1 more source
In the Interval of the Wave: Prince Edward Island Women\u27s Nineteenth- and Early Twentieth-Century Life Writing by Mary McDonald-Rissanen [PDF]
, 2015 Review of In the Interval of the Wave: Prince Edward Island Women\u27s Nineteenth- and Early Twentieth-Century Life Writing by Mary McDonald ...
Bartlett, Joshua
core +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Scientific Reports, 2017 Shell microstructure and mineralogy of Pelagiella madianensis Zhou & Xiao, 1984, a globally distributed Cambrian micromollusk, are investigated based on abundant and extraordinarily well-preserved specimens from Xinji Formation, Longxian, Shaanxi, North ...
Luoyang Li +3 more
doaj +1 more source