Results 161 to 170 of about 19,801,094 (386)
Early-life lead exposure and neurodevelopmental disorders
, 2021 Damaris Albores‐García +2 more
openalex +2 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Patterns of farm exposure are associated with reduced incidence of atopic dermatitis in early life
, 2020 Cheryl A. Steiman +9 more
openalex +2 more sources
From early life to senescence: individual heterogeneity in a long‐lived seabird [PDF]
, 2017 Rémi Fay +3 more
openalex +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
One and one makes three—mothers' and fathers' attachment, mentalizing and parenting sensitivity
Frontiers in PsychologyObjectiveThis study aims to explore how maternal and paternal attachment representations and their reflective functioning (RF), as operationalization of their mentalizing abilities, influence each other's parental sensitivity within a family systems ...
Selina Ismair +11 more
doaj +1 more source
Early life cognitive development trajectories and intelligence quotient in middle childhood and early adolescence in rural western China [PDF]
, 2019 Zhonghai Zhu +10 more
openalex +1 more source
Simtech 08 poster submission: digital upheavals: ethnographic studies on digital-DIY activity [PDF]
, 2008 This poster describes current work-in-progress on a digital-DIY research project, exploring how people experiencing life-change configure and re-configure their domestic entertainment, information and communication technologies.
Ely, Philip
core +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
The Technology of Skill Formation [PDF]
his paper presents formal models of child development that capture the essence of recent findings from the empirical literature on child development.
Flavio Cunha +2 more
core