Results 161 to 170 of about 20,037,007 (385)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Maternal preconception body mass index and offspring cord blood DNA methylation: Exploration of early life origins of disease

open access: green, 2013
Xin Liu   +16 more
openalex   +2 more sources

Progress in European CELSS activities [PDF]

open access: yes
The European Controlled Ecological Life Support System (CELSS) activities started in the late 1970's with system analysis and feasibility studies of Biological Life Support Systems (BLSS).
Skoog, A. I.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Immunization of sheep against GnRH early in life: effects on reproductive function and hormones in rams [PDF]

open access: bronze, 1994
B. W. Brown   +6 more
openalex   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

One and one makes three—mothers' and fathers' attachment, mentalizing and parenting sensitivity

open access: yesFrontiers in Psychology
ObjectiveThis study aims to explore how maternal and paternal attachment representations and their reflective functioning (RF), as operationalization of their mentalizing abilities, influence each other's parental sensitivity within a family systems ...
Selina Ismair   +11 more
doaj   +1 more source

Distinct Localization, Transcriptional Profiles, and Functionality in Early Life Tonsil Regulatory T Cells [PDF]

open access: green
S Verma   +11 more
openalex   +1 more source

Life-Detection Technologies for the Next Two Decades

open access: yes, 2018
Since its inception six decades ago, astrobiology has diversified immensely to encompass several scientific questions including the origin and evolution of Terran life, the organic chemical composition of extraterrestrial objects, and the concept of ...
Bodas, Dhananjay   +22 more
core  

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